The 6-OHDA was purchased from Sigma-Aldrich (St. Louis, MO, USA). D-amphetamine was provided by the NIDA Drug Supply Program. GW842166X and AM630 were purchased from Cayman Chemical Company (Ann Arbor, MI, USA). GW842166X and AM630 were first dissolved in DMSO (Sigma-Aldrich) and then mixed with TWEEN-80 (Sigma-Aldrich). Then, sterile saline was added to the mix solution to create a final working solution with 2.5% DMSO + 2.5% TWEEN-80 + 95% saline. Picrotoxin and all other common chemicals were obtained from Sigma-Aldrich. 6-Cyano-7-nitroquinoxaline-2,3-dione disodium salt (CNQX) and D-(-)-2-Amino-5-phosphonopentanoic acid (D-AP5) were obtained from Tocris Bioscience (Ellisville, MO, USA).
Gw842166x
Manufactured by Merck Group
Sourced in United States
GW842166X is a laboratory product manufactured by Merck Group. It is a chemical compound used for research and experimental purposes. The core function of this product is to serve as a tool for scientific investigations and studies. Detailed information about its specific applications or intended use is not available.
Automatically generated - may contain errors
Lab products found in correlation
Am630, by Merck Group (2 mentions)
Gw842166x, by Cayman Chemical (2 mentions)
6 ohda, by Merck Group (2 mentions)
Am630, by Cayman Chemical (2 mentions)
Picrotoxin, by Merck Group (1 mentions)
6 cyano 7 nitroquinoxaline 2 3 dione disodium salt cnqx, by Bio-Techne (1 mentions)
D 2 amino 5 phosphonopentanoic acid d ap5, by Bio-Techne (1 mentions)
Dimethyl sulfoxide (dmso), by Merck Group (1 mentions)
Tween 80, by Merck Group (1 mentions)
Peg 200, by Electron Microscopy Sciences (1 mentions)
Cremophor el, by Merck Group (1 mentions)
2 protocols using gw842166x
1
6-OHDA-Induced Neurodegeneration Model
2
6-OHDA Model of Parkinson's Disease
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The sources of chemicals were the following: 6-OHDA, (Sigma-Aldrich, St. Louis, MO, USA); GW842166X and AM630, (Cayman Chemical Company, Ann Arbor, MI, USA. 35% PEG 200 (Electron Microscopy Sciences, Hatfield, PA, USA), 10% cremophor EL (Sigma-Aldrich, St. Louis, MO, USA), and 55% sterile saline with gentle heating was used as the vehicle for GW842166X and AM630 [49 (link)]. All other common chemicals were obtained from Sigma-Aldrich (St. Louis, MO, USA).
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!