Transcutol cg

Manufactured by Gattefosse

Sourced in Spain, France

Transcutol CG is a high-purity solvent and co-solvent used in pharmaceutical and cosmetic formulations. It is a clear, colorless, odorless liquid with a high boiling point and low volatility. Transcutol CG is miscible with water and a wide range of organic solvents.

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Lab products found in correlation

Hesperetin, by Merck Group (1 mentions) Labrasol, by Gattefosse (1 mentions) Labrafac, by Gattefosse (1 mentions)

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Transcutol (28 citations)

2 protocols using transcutol cg

Hesperetin Topical Formulation Development

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Hesperetin (>95% purity) obtained from Sigma-Aldrich (Steinheim production, Steinheim, Germany) was used as the active ingredient. The semi-solid vehicle was prepared using the following compounds: Phospholipid S75 (Lipoid^®, Abaran Materias Primas S.L., Madrid, Spain), Almond oil (Acofarma^®, Barcelona, Spain), and Transcutol CG (Gattefossé^®, Neuilly-Sur-Seine, France). Polysorbate 80, tocopherol, cetostearyl alcohol, propylene glycol, ethanol, methylparaben, propylparaben, and hyaluronic acid of low molecular weight were obtained from Guinama^® (Valencia, Spain), and MilliQ water was also used.

Taléns-Visconti R., Belarbi Y., Díez-Sales O., de Julián-Ortiz J.V., Vila-Busó O, & Nácher A. (2024). A New Hyaluronic Emulgel of Hesperetin for Topical Application—An In Vitro Evaluation. Journal of Functional Biomaterials, 15(4), 89.

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Formulation Excipients for Transdermal Delivery

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Labrasol^® (caprylocaproyl macrogol-8-glyceride/caprylocaproyl polyoxyl-8 glycerides), Transcutol CG^® (diethylene glycol monoethyl ether), and Labrafac^® (propylene glycol dicaprylocaprate) were purchased from Gattefosse (St. Priest, France). Propylene glycol and ethanol were purchased from Sigma–Aldrich^® (St. Louis, MO, USA). All excipients were used as provided without further purification. Ultrapure water quality was obtained from Milli-Q^® purification system and was used in this study.

Forouz F., Dabbaghi M., Namjoshi S., Mohammed Y., Roberts M.S, & Grice J.E. (2020). Development of an Oil-in-Water Self-Emulsifying Microemulsion for Cutaneous Delivery of Rose Bengal: Investigation of Anti-Melanoma Properties. Pharmaceutics, 12(10), 947.

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