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Kolliphor ps80

Manufactured by BASF
Sourced in Germany

Kolliphor PS80 is a non-ionic surfactant used in various pharmaceutical and cosmetic applications. It is a polyoxyethylene sorbitan monooleate derivative that can act as a solubilizing agent, emulsifier, and wetting agent. The core function of Kolliphor PS80 is to improve the solubility and stability of active ingredients in formulations.

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5 protocols using kolliphor ps80

1

Nanomicellar Coumarin C6 Formulation

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NCL was purchased from Biosynth-Carbosynth (San Diego, CA). Eudragit EPO and Eudragit S100 (Evonik Corporation, Los Angeles, CA), polyvinylacetate phthalate (Colorcon, West Point, PA), and Vitamin E TPGS NF grade (Antares Health Products, Jonesborough, TN) were received as gift samples. Poloxamer 407 (Kolliphor P407), Poloxamer 188 (Kolliphor P188), Kolliphor ELP, Kolliphor RH40, Kolliphor HS15, Kolliphor PS80, and Kolliphor PS20 were obtained as gift samples from BASF (Florham Park, NJ). Acetone (AR Grade), scintillation vials (7 ml and 20 ml), and Coumarin C6 were purchased from VWR International (Radnor, PA). Ultrapure distilled water was used for all experiments.
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2

Formulation Development of Lipid-based Drug Delivery

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DFX was kindly gifted from Sanovel Drug Company, Turkey. Labrafac, Lipophile WL1349, Labrafac PG, Peceol, Transcutol HP, Labrasol ALF, Labrafil M2125, Maisine, Gelucire 44/14 and Gelucire 48/16 were kindly gifted from Gatteffosse (Lyon, France). Kolliphor PS20, Kolliphor PS60, Kolliphor PS80, Kolliphor CS12 and Kolliphor HS15, Kolliphor EL, Kolliphor ELP, and Kollisov PEG 400 were kindly gifted from BASF (Ludwigshafen, Germany). Syloid XDP 3150 was gifted from Grace (Columbia, Maryland, USA). Neusilin UFL2 and Neusilin US2 were gifted from Fuji chemical (Tokyo, Japan). All other chemicals were of analytical grade.
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3

Formulation of Lipid-Based Drugs

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PPD (purity >99.9%, Figure 1) was purchased from Chengdu Biopurify Phytochemicals, Ltd. (Chengdu, China). Kolliphor HS15 (polyoxyl 15 hydroxystearate), Kolliphor EL (polyoxyl castor oil), Kolliphor PS 80 (polysorbate 80), and Kollisolv MCT 70 (medium chain triglycerides) were provided by BASF (Ludwigshafen, Germany). Capmul MCM C8 (mono/diglycerides of caprylic acid) and Capryol 90 (propylene glycol monocaprylate (type II) were provided by Gattefosse (Saint-Priest, France). All other chemicals were of reagent grade and were used without further purification.
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4

Formulation and Characterization of Lipid-Based Nano-Carriers

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PZH was purchased from Hangzhou Royall Import and Export Co., Ltd. (Hangzhou, China). Kolliphor EL (polyoxyl 35 castor oil), Kolliphor HS15 (polyoxyl 15 hydroxystearate), Kolliphor RH40 (polyoxyl 40 hydrogenated castor oil), Kolliphor PS80 (polysorbate 80), Kollisolv PG (propylene glycol), Kollisolv MCT70 (medium-chain triglyceride), and Kollisolv PEG400 (polyethylene glycol 400) were provided by BASF (Ludwigshafen, Germany). Capmul MCM C8 (glyceryl monocaprylate) and Capmul MCM C10 (glyceryl monocaprate) were provided by ABITEC (Columbus, OH, USA). Castor oil was provided by DongYang Oil Chemical (Anseong, Korea). All other chemicals were of reagent grade and were used without further purification.
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5

Formulation Development of Alectinib Hydrochloride

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Alectinib hydrochloride was purchased from Wuhan Vanz Pharm Inc. (Wuhan, China). Kolliphor HS 15 (polyoxyl 15 hydroxy stearate), Kollisolv PEG 300 (polyethylene glycol 300), Kollisolv PEG 400 (polyethylene glycol 400), Kolliphor EL (polyoxyl 35 castor oil), Kolliphor PS 20 (Polysorbate 20), Kolliphor PS 80 (polysorbate 80), Kolliphor RH 40 (polyoxyl 40 hydrogenated castor oil), and Kollisolv MCT 70 (medium-chain capric triglyceride) were kindly provided by BASF (Ludwigshafen, Germany). Transcutol P (diethylene glycol monoethyl ether) and Capryol 90 (propylene glycol monocaprylate (type II)) were kindly provided by Gattefosse (Saint-Priest, France). Capmul MCM C8 (mono/diglycerides of caprylic acid) and Capmul MCM C10 (mono/diglycerides of capric acid) were kindly provided by ABITEC Corporation (Janesville, WI, USA). Sodium lauryl sulfate (SLS) was kindly provided by DUKSAN Pure Chemical (Ansan, Korea). All other chemicals were of reagent grade and were thus used without further purification.
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