C57BL/6, 129X1/SvJ, Bcl2l11−/−, Il1r−/− and CD11c-Cre mice were from The Jackson Laboratory. Stat3-deficient DCs were generated by crossing Stat3-floxed mice with CD11c-Cre mice16 (link). Il21r−/− mice have been described10 (link). Ripk3 and Casp8 double deficient mice have been described24 (link). Casp1−/− mice were from The Jackson Laboratory or from Dr. Richard Flavell, Yale University32 (link). Nlrp3−/− and Pycard−/− mice were from Dr. Vishva Dixit, Genentech33 (link), 34 (link). Both male and female mice from 7 to 12 weeks old were used. All protocols were approved by the NHLBI Animal Care and Use Committee and followed NIH guidelines for using animals in intramural research. MLN120B was provided by Dr. Ulrich Siebenlist, NIH.
Bcl2l11
Manufactured by Jackson ImmunoResearch
Bcl2l11−/− is a gene knockout mouse model. It is used in research to study the function of the Bcl2l11 gene, which is involved in the regulation of apoptosis, or programmed cell death.
Automatically generated - may contain errors
2 protocols using bcl2l11
1
Murine Immunology Protocols: Transgenic Mice
2
Genetically Modified Mouse Models
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C57BL/6, 129X1/SvJ, Bcl2l11−/−, Il1r−/− and CD11c-Cre mice were from The Jackson Laboratory. Stat3-deficient DCs were generated by crossing Stat3-floxed mice with CD11c-Cre mice16 (link). Il21r−/− mice have been described10 (link). Ripk3 and Casp8 double-deficient mice have been described24 (link). Casp1−/− mice were from The Jackson Laboratory or from Dr Richard Flavell, Yale University32 (link). Nlrp3−/− and Pycard−/− mice were from Dr Vishva Dixit, Genentech33 (link)34 (link). Both male and female mice from 7 to 12 weeks old were used. All protocols were approved by the NHLBI Animal Care and Use Committee and followed NIH guidelines for using animals in intramural research. MLN120B was provided by Dr Ulrich Siebenlist, NIH.
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