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Clone yigif74 1g7

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The Clone YIGIF74-1G7 is a laboratory equipment product. It serves as a core functional component for various scientific applications. The specific details and intended use of this product are not available at this time.

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Lab products found in correlation

Clone afs98, by BioXCell (2 mentions) Ifnγ clone xmg1.2, by BioXCell (2 mentions) Clone 1a8, by BioXCell (2 mentions) Clone 2, by BioXCell (2 mentions)

2 protocols using clone yigif74 1g7

1

Immune Cell Depletion and Cytokine Neutralization

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Depletions of immune cells were done using antibodies against CD8α (clone 2.43, BioXCell 400 ug i.p. twice weekly), NK1.1 (clone PK136, BioXCell, 400 ug i.p. twice weekly), Ly6g (clone 1A8, BioXCell, 400 ug i.p. twice weekly) or CSF1R (clone AFS98, BioXCell, 300 ug i.p. every other day) as previously described26 (link). Cytokine neutralization was done using i.p. treatments with 200 ug of antibodies against IFN-γ (clone XMG1.2, BioXCell), IL1β (clone B122, BioXCell) and IL18 (clone YIGIF74-1G7, BioXCell) every other day. All depletion antibodies dosing was initiated one day before i.t. treatment and continued till atleast 1 month after treatment.
Agarwal Y., Milling L.E., Chang J.Y., Santollani L., Sheen A., Lutz E.A., Tabet A., Stinson J., Ni K., Rodrigues K.A., Moyer T.J., Melo M.B., Irvine D.J, & Wittrup K.D. (2022). Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity. Nature biomedical engineering, 6(2), 129-143.
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2

Immune Cell Depletion and Cytokine Neutralization

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
Depletions of immune cells were done using antibodies against CD8α (clone 2.43, BioXCell 400 ug i.p. twice weekly), NK1.1 (clone PK136, BioXCell, 400 ug i.p. twice weekly), Ly6g (clone 1A8, BioXCell, 400 ug i.p. twice weekly) or CSF1R (clone AFS98, BioXCell, 300 ug i.p. every other day) as previously described26 (link). Cytokine neutralization was done using i.p. treatments with 200 ug of antibodies against IFN-γ (clone XMG1.2, BioXCell), IL1β (clone B122, BioXCell) and IL18 (clone YIGIF74-1G7, BioXCell) every other day. All depletion antibodies dosing was initiated one day before i.t. treatment and continued till atleast 1 month after treatment.
Agarwal Y., Milling L.E., Chang J.Y., Santollani L., Sheen A., Lutz E.A., Tabet A., Stinson J., Ni K., Rodrigues K.A., Moyer T.J., Melo M.B., Irvine D.J, & Wittrup K.D. (2022). Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity. Nature biomedical engineering, 6(2), 129-143.
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