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Sitagliptin phosphate

Manufactured by LGC
Sourced in Canada, United States

Sitagliptin phosphate is a pharmaceutical compound used as an active ingredient in various medications. It functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, which helps regulate blood glucose levels in individuals with type 2 diabetes. The core function of sitagliptin phosphate is to enhance the activity of incretin hormones, leading to improved glycemic control.

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2 protocols using sitagliptin phosphate

1

Investigating Molecular Pathways in Metabolism

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T0901317, 9-cis-retinoic acid, phorbol 12-myristate 13-acetate (PMA), GLP-1 (7–37), and exendin-(9–39) were purchased from Sigma (St Louis, MO, USA). Endotoxin, fatty-acid-free bovine serum albumin (BSA), and the PKA inhibitor 14–22 amide were purchased from Calbiochem (Merck KGaA, Darmstadt, Germany). Sitagliptin phosphate and vildagliptin were purchased from Toronto Research Chemicals Inc. (Toronto, ON, Canada).
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2

Quantification of Metformin and Antidepressants

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Unlabeled metformin was purchased from Wako Pure Chemical Industries (Osaka, Japan), and [ 14 C]metformin (100 mCi/mmol) was purchased from Moravek Biochemicals (Brea, CA, USA). Unlabeled almotriptan malate was purchased from Sigma (St. Louis, MO, USA).
Unlabeled alogliptin, naratriptan hydrochloride, rivaroxaban, saxagliptin, sitagliptin phosphate, sumatriptan succinate, talinolol and vildagliptin were purchased from Toronto Research Chemicals (Toronto, Ontario, Canada). All other chemicals and reagents were of analytical grade and are commercially available.
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