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Sch 23390

Manufactured by Abcam
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SCH-23390 is a laboratory product that functions as a selective antagonist for the dopamine D1 receptor. It is commonly used in research applications to study the role of the dopamine D1 receptor in various biological processes.

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Lab products found in correlation

Skf 81297, by Hello Bio (2 mentions) Quinine, by Merck Group (2 mentions) Methysergide, by Merck Group (2 mentions) Dopamine, by Merck Group (2 mentions) Yohimbine, by Abcam (2 mentions) Citalopram, by Abcam (2 mentions) Gr 127935, by Abcam (2 mentions) Kynurenic acid, by Hello Bio (2 mentions) Cgp 55845, by Hello Bio (2 mentions) Gabazine, by Abcam (2 mentions) Kynurenic acid, by Merck Group (2 mentions)

4 protocols using sch 23390

1

Psychostimulant drug administration protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Ethanol (Decon Laboratories, 190 proof, in glass container) was dissolved in tap water at 20% v/v. Quinine (Sigma-Aldrich) was dissolved in 20% alcohol. SCH-23390 (abcam) and SKF-81297 (hello bio) were dissolved in saline. Intraperitoneal (i.p.) drug administration was delivered at 10 ml/kg body weight.
Bocarsly M.E., da Silva e Silva D., Kolb V., Luderman K.D., Shashikiran S., Rubinstein M., Sibley D.R., Dobbs L.K, & Alvarez V.A. (2019). A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors. Cell reports, 29(5), 1147-1163.e5.
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2

Dopamine Solution Preparation and Compound Sourcing

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Dopamine solutions were made fresh daily and kept covered in aluminum foil and on ice to minimize oxidation. All other agonist and antagonists were prepared as stock solutions (1:1000-1:10,000) in DI water or dimethylsulfoxide (DMSO) and diluted into ACSF prior to experiments. The bath concentration of Rubi-GABA perfusion was 10 μM. Cocaine HCl was obtained from the National Institute on Drug Abuse. Dopamine, NEM, kynurenic acid, and methysergide were obtained from Sigma. CPP, gabazine, SCH-23390, yohimbine, citalopram, and GR 127935 were obtained from Abcam. CGP 55845 was obtained from Hello Bio Inc. NBQX was obtained from Hello Bio Inc. and Abcam. kynurenic acid was obtained from Hello Bio and Sigma. All other drugs were obtained from Tocris.
Burke D.A, & Alvarez V.A. (2022). Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports, 39(6), 110795.
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3

Psychostimulant drug administration protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Ethanol (Decon Laboratories, 190 proof, in glass container) was dissolved in tap water at 20% v/v. Quinine (Sigma-Aldrich) was dissolved in 20% alcohol. SCH-23390 (abcam) and SKF-81297 (hello bio) were dissolved in saline. Intraperitoneal (i.p.) drug administration was delivered at 10 ml/kg body weight.
Bocarsly M.E., da Silva e Silva D., Kolb V., Luderman K.D., Shashikiran S., Rubinstein M., Sibley D.R., Dobbs L.K, & Alvarez V.A. (2019). A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors. Cell reports, 29(5), 1147-1163.e5.
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4

Dopamine Solution Preparation and Compound Sourcing

Check if the same lab product or an alternative is used in the 5 most similar protocols
Dopamine solutions were made fresh daily and kept covered in aluminum foil and on ice to minimize oxidation. All other agonist and antagonists were prepared as stock solutions (1:1000-1:10,000) in DI water or dimethylsulfoxide (DMSO) and diluted into ACSF prior to experiments. The bath concentration of Rubi-GABA perfusion was 10 μM. Cocaine HCl was obtained from the National Institute on Drug Abuse. Dopamine, NEM, kynurenic acid, and methysergide were obtained from Sigma. CPP, gabazine, SCH-23390, yohimbine, citalopram, and GR 127935 were obtained from Abcam. CGP 55845 was obtained from Hello Bio Inc. NBQX was obtained from Hello Bio Inc. and Abcam. kynurenic acid was obtained from Hello Bio and Sigma. All other drugs were obtained from Tocris.
Burke D.A, & Alvarez V.A. (2022). Serotonin receptors contribute to dopamine depression of lateral inhibition in the nucleus accumbens. Cell reports, 39(6), 110795.
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