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Bio voc sampler

Manufactured by Markes International
Sourced in United Kingdom, United States

The Bio-VOC™ sampler is a compact and portable device designed for the collection of volatile organic compounds (VOCs) from human breath. It allows for the capture of breath samples for subsequent analysis using analytical techniques such as gas chromatography-mass spectrometry (GC-MS).

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Lab products found in correlation

3 protocols using bio voc sampler

1

Acute Biological Response to Chlorinated Pool Exposure

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The PISCINA II study is an experimental investigation of the acute biological response to exposures induced by swimming in a chlorinated pool. As detailed elsewhere,31 (link) the study included volunteers, aged 18–40 years, non-smoking and non-professional swimmers, who swam for 40 min in a 25 m long indoor chlorinated pool in Barcelona, Spain, between June and December 2013. At the time of the experiment, participants were asked to complete a questionnaire providing information on sociodemographic, dietary habits, regular physical activity, medical and anthropometric factors.
DBPs including four THMs, CHCl3, BDCM, DBCM and CHBr3, were measured in exhaled breath at two time points: before swimmers entered the swimming pool and immediately after they exited the swimming pool, using the Bio-VOC Sampler (Markes International Ltd, UK). These chemicals were assessed by gas chromatography coupled to a mass spectrometer. Details on sampling collection and analysis have been published previously.31 (link)
For each of these 60 participants with full exposure and questionnaire data, two blood samples collected before and 2 hours after swimming were available. These were collected in a room detached from the swimming pool area and stored at −80°C.
Informed consent was provided by each participant before commencement of the experiment.
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2

Firefighter Exhaled Breath Sampling

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Exhaled breath samples were collected from firefighters before and immediately after each fire (n = 144 person events). Collections took place inside a laboratory building upwind of the FES and well after fire suppression was complete. Firefighters were instructed to take a deep breath in and then forcefully exhale their entire breath into the Bio-VOC sampler (Markes International, Inc., Cincinnati, OH), which serves to collect 129-mL of breath. This process was then repeated, resulting in 258-ml of breath for each sample collection. The collected air was pushed through Markes thermal desorption tubes (Carbograph 2TD/1TD dual bed tubes). The thermal desorption tubes were capped and stored at -20 °C until shipment to the U.S. Environmental Protection Agency (EPA) analytical laboratory. A field blank was collected during each sample collection period.
The method used to analyze the breath samples is described in detail elsewhere (Geer Wallace et al. 2017 (link)). Method detection limits (MDLs) ranged from 0.70 ng/tube for benzene to 1 ng/tube for toluene. The ng on tube was converted to ng/L by dividing by the total breath volume collected (0.258 L) and results are reported as parts per billion volume (ppbv).
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3

Exhaled Breath Analysis for Uptake Monitoring

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Exhaled breath can be used to assess volatile fraction of the systemic uptake, regardless of route of entry (presumably dermal in this case) (Pleil and Lindstrom, 1998 (link); Pleil, 2008 ). We measured the concentrations of combustion products in exhaled breath samples collected pre-, post-, and 6-h post-exposure. The firefighters were instructed to take a deep breath in and then forcefully exhale into the Bio-VOC™ sampler (Markes International, Wilmington, DE, USA) until they had fully expired their breath, permitting the sampler to collect alveolar air. We then pushed the collected alveolar air through Markes Carbograph 2TD/Carbograph 1TD thermal desorption tubes using a plunger. The samples were analyzed for aromatic hydrocarbons (benzene, toluene, ethyl benzene, xylene, and styrene) and semi-volatile PAHs (naphthalene, anthracene, phenanthrene, fluoranthene, and pyrene) using a gas chromatography/mass spectrometry (GC/MS) method described in Sobus et al. (2008) (link).
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