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Merci retriever

Manufactured by Stryker
Sourced in Ireland

The Merci Retriever is a medical device designed for the removal of blood clots from the brain during ischemic stroke procedures. It functions as a catheter-based system that can be used to capture and extract clots from occluded blood vessels.

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2 protocols using merci retriever

1

Mechanical Thrombectomy for Acute Ischemic Stroke

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All consecutive acute ischemic stroke patients with large-vessel occlusion treated by mechanical thrombectomy at a single academic institution between August 2002 and October 2012 were identified from a prospectively maintained database. Patients treated with thrombectomy were either ineligible for IV tPA or refractory to thrombolysis after receiving IV tPA within 4.5 h of stroke onset.3 (link),19 (link) The mechanical clot retrieval devices included Merci Retriever (Stryker neurovascular, Mountain View, CA), Penumbra System (Penumbra, Inc., Alameda, CA), stent retriever with Solitaire FR device (Covidien/eV3, Dublin, Ireland), or Trevo Retriever (Stryker neurovascular).
Magnetic resonance imaging (MRI) before thrombectomy was routinely performed in all patients without selection biases unless contraindicated. Patients also typically underwent follow-up magnetic resonance (MR) within 48 h after thrombectomy. The multimodal MRI protocol included diffusion-weighted imaging, perfusion-weighted imaging, T2∗ gradient-recall echo (GRE), and fluid-attenuated inversion recovery (FLAIR) sequences. We included patients who had serial T2∗ GRE before and 48 h after thrombectomy. The local institutional review board of University of California at Los Angeles approved the study. Informed consent was obtained from the patient or their representative.
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2

Efficacy of Mechanical Thrombectomy Devices

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We analyzed data from the Multi MERCI, TREVO, and TREVO 2 trials, in which the Merci Retriever (Stryker Neurovascular, Mountain View, CA) and the Trevo Retriever (Stryker Neurovascular) were used.4 (link),6 (link),8 (link) The databases of all 3 trials were maintained at Stryker Neurovascular. Appropriate institutional review board or ethics committees approvals were obtained by participating centers in all 3 trials. All 3 trials enrolled patients with acute ischemic stroke who were either ineligible for or refractory to IV tPA. Endovascular thrombectomy therapy was initiated within 8 hours of symptom onset.
All 3 trials included patients with angiographically confirmed intracranial vessel occlusion in both anterior and posterior circulations. All patients were older than 18 years with National Institutes of Health Stroke Scale (NIHSS) score of greater than 8. The TREVO and TREVO 2 trials had age limit of 85 years and NIHSS score upper limit of 30 and 29, respectively. In the Multi MERCI trial, IV tPA was allowed within 3 hours after symptom onset. A 4.5-hour time window was used for IV tPA in the TREVO and TREVO 2 trials.
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