Ge definium 8000

Manufactured by GE Healthcare

Sourced in United Kingdom

The GE Definium 8000 is a diagnostic imaging system designed for radiographic examinations. It provides high-quality digital images to support healthcare professionals in their patient care activities.

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Lab products found in correlation

Volumerad, by GE Healthcare (1 mentions) Biograph mct 40, by Siemens (1 mentions) Volumerad option, by GE Healthcare (1 mentions)

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Definium 8000 (11 citations)

3 protocols using ge definium 8000

Dose-Optimized Thoracic Screening with DTS

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DTS examinations were performed with the commercially available X-ray system GE Definium 8000, with the VolumeRAD option (GE Healthcare, Chalfont St Giles, UK). Sixty low-dose projection radiographs were acquired during a caudo-cranial tube movement of 30° during a 10-s breath hold at full inspiration, with standard acquisition parameters recommended for DTS (26 (link)). The low-dose projections were reconstructed to approximately 60 coronal section images with a reconstruction interval of 5 mm. No retakes were allowed due to radiation considerations. Effective dose for the 70 kg standard patient was estimated by multiplying the dose-area product (DAP) by 0.26 mSvGy^–1 cm^–2 (27). DAP was calculated from data in the digital imaging and communications in medicine (DICOM) header of the scout image (28 (link)).

Meltzer C., Fagman E., Vikgren J., Molnar D., Borna E., Beni M.M., Brandberg J., Bergman B., Båth M, & Johnsson Å.A. (2020). Surveillance of small, solid pulmonary nodules at digital chest tomosynthesis: data from a cohort of the pilot Swedish CArdioPulmonary bioImage Study (SCAPIS). Acta Radiologica (Stockholm, Sweden : 1987), 62(3), 348-359.

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In Vivo Biodistribution and Contrast Imaging

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For investigation of biodistribution and contrast properties in vivo, Biograph mCT40 (Siemens) and GE Definium 8000 systems (GE Healthcare) were used. Briefly, tumors based on B16-F10 mouse melanoma cells were grafted onto the mice.
Then, BaCO 3 MPs, BaCO 3 NPs and iohexol were separately injected into the tumor and the tail vein (100 mg kg À1 ).
Analyses of biodistribution and contrasting were performed at different time points. The signal intensity of organs and tumors was processed using the DICOM editor and ImageJ software.
The signal intensity was represented in a.u. The details and full data are presented in the ESI. † 2.12. SPECT imaging SPECT analysis was carried out using SPECT Discovery NM 630 system (GE Healthcare). The BaCO 3 particles were radiolabeled as described above. Then, the radiolabeled particles were injected into C57BL/6 mice with subcutaneous tumors (10 MBq, 100 mg kg À1 ). To visualize the anatomy of mice and localization of SPECT signals, digital outlines of mice were used for further data formation. The SPECT images were superimposed on the outlines and analyzed using an image editor with a merge function. The details are presented in the ESI. †

Karpov T., Darwish A., Mitusova K., Postovalova A., Akhmetova D., Vlasova O., Shipilovskikh S., & Timin A. (2024). Controllable synthesis of barium carbonate nano- and microparticles for SPECT and CT imaging. Journal of Materials Chemistry B, 12(17), 4232-4247.

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Low-Dose CT Protocol for Carpal Tunnel Syndrome

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The Regional Ethical Review Board approved this study and all participants gave written informed consent. Pathologyfree CTS examinations from twenty-four patients (male, n = 14), with age between 22 and 77 years (average 49.9 years) were included in the study. Some of the included examinations have previously been used in CTS studies with other purpose (10, 15) . The CTS examinations were performed using GE Definium 8000 with VolumeRAD option (GE Healthcare, Chalfont St Giles, UK). For each examination, sixty low-dose projection images were collected within an angular interval of §15°around the posteroanterior (PA) projection. The projection images were collected using a tube voltage of 120 kV and an additional filtration of 3 mm Al + 0.1 mm Cu and the image acquisition time was approximately 10 seconds. The tube load (mAs) used for the collection of each projection image was determined from a PA scout image, which was collected using automatic exposure control and the dose ratio 1:10. These default exposure settings results in an effective dose of 0.12 mSv (0.13 mSv scout view included) for an average-sized patient (3).

Mirzai M., Meltzer C., Vikgren J., Norrlund R.R., Gottfridsson B., Johnsson Å., Båth M, & Svalkvist A. (2021). The Effect of Dose Reduction on Overall Image Quality in Clinical Chest Tomosynthesis. Academic radiology, 28(10).

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