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Deuterated choline chloride

Manufactured by Merck Group
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Deuterated choline chloride is a stable isotope compound used as a labeling agent in analytical and biochemical applications. It serves as a precursor for the synthesis of deuterated biomolecules.

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Lab products found in correlation

Deuterium oxide, by Avantor (2 mentions) Deuterated d glucose, by Merck Group (2 mentions)

2 protocols using deuterated choline chloride

1

Deuterium Labelling for Metabolic Study

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For metabolic labelling, the standard cell culture medium was adapted as follows: (i) supplementation with 1 mM deuterated choline chloride (492051, Sigma), (ii) substitution of D-glucose with 50% (w/w, or 2.25 g L−1) deuterated D-glucose (552003, Sigma), and (iii) substitution of H2O with 50% (v/v) deuterium oxide (D2O, VWR International Ltd, Lutterworth, UK).
Horgan C.C., Nagelkerke A., Whittaker T.E., Nele V., Massi L., Kauscher U., Penders J., Bergholt M.S., Hood S.R, & Stevens M.M. (2020). Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling. Journal of materials chemistry. B, 8(20), 4447-4459.
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2

Deuterium Labelling for Metabolic Study

Check if the same lab product or an alternative is used in the 5 most similar protocols
For metabolic labelling, the standard cell culture medium was adapted as follows: (i) supplementation with 1 mM deuterated choline chloride (492051, Sigma), (ii) substitution of D-glucose with 50% (w/w, or 2.25 g L−1) deuterated D-glucose (552003, Sigma), and (iii) substitution of H2O with 50% (v/v) deuterium oxide (D2O, VWR International Ltd, Lutterworth, UK).
Horgan C.C., Nagelkerke A., Whittaker T.E., Nele V., Massi L., Kauscher U., Penders J., Bergholt M.S., Hood S.R, & Stevens M.M. (2020). Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling. Journal of materials chemistry. B, 8(20), 4447-4459.
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