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B6n 129 cg

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B6N.129(Cg)- is a mouse strain used for immunological research. It is a congenic strain developed on the C57BL/6N background, with a targeted mutation in the Cg gene. The Cg gene is involved in the production of melanin pigment, and the mutation results in the absence of pigmentation in these mice.

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Lab products found in correlation

B6 cg tg, by Jackson ImmunoResearch (2 mentions) Stat5btm2mam mmjax, by Jackson ImmunoResearch (2 mentions) B6 cg tg cd4 cre 1cwi cd4 cre, by Taconic Biosciences (2 mentions) B6 cg, by Jackson ImmunoResearch (2 mentions) C57bl 6j, by Jackson ImmunoResearch (2 mentions)

2 protocols using b6n 129 cg

1

Generation of Transgenic Mouse Strains

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The following mouse strains used were purchased from Jackson Laboratory and/or bred at our facility: C57BL/6J (B6); B6.129P2-Tcrbtm1Mom/J (Tcrb−/−); B6.129S2-Il1btm1Dch (Il1b−/−); B6.Cg-Tg-Il17ftm1(Thy1)Weav (Il17fthy1.1); B6.Cg-Tg(TcraTcrb)425Cbn/J (OT-II); B6N.129(Cg)-Foxp3tm3Ayr/J (Foxp3gfp); B6.129S7-Il1r1tm1Imx/J (Il1r1−/−); B6.129S6-Stat5a-Stat5btm2Mam/Mmjax (Stat5fl/fl); B6.129S1-Relafl/fl (Relafl/fl); B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J (Rosa26TdTomato fl/+); and B6.129S4-Socs3tm1Ayos/J (Socs3fl/fl). B6.Cg-Tg(Cd4-Cre)1Cwi (Cd4-Cre) were purchased from Taconic and B6.CD45.1 from Frederick Cancer Center. All strains were on a B6 background. All intercrosses to generate additional strains like WT and IL-1R-deficient dual reporter mice (Il17fthy1.1.Foxp3gfp), Il17fthy1.1.CD45.1/CD45.2 and Stat5bfl/fl. Cd4-Cre mice were generated by crosses in our breeding facility. Animals were bred and maintained under specific pathogen-free condition in accordance with institutional animal care and use committee regulations.
Basu R., Whitley S.K., Bhaumik S., Zindl C.L., Schoeb T.R., Benveniste E.N., Pear W.S., Hatton R.D, & Weaver C.T. (2015). IL-1 signaling modulates STAT activation to antagonize retinoic acid signaling and control Th17–iTreg balance. Nature immunology, 16(3), 286-295.
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2

Generation of Transgenic Mouse Strains

Check if the same lab product or an alternative is used in the 5 most similar protocols
The following mouse strains used were purchased from Jackson Laboratory and/or bred at our facility: C57BL/6J (B6); B6.129P2-Tcrbtm1Mom/J (Tcrb−/−); B6.129S2-Il1btm1Dch (Il1b−/−); B6.Cg-Tg-Il17ftm1(Thy1)Weav (Il17fthy1.1); B6.Cg-Tg(TcraTcrb)425Cbn/J (OT-II); B6N.129(Cg)-Foxp3tm3Ayr/J (Foxp3gfp); B6.129S7-Il1r1tm1Imx/J (Il1r1−/−); B6.129S6-Stat5a-Stat5btm2Mam/Mmjax (Stat5fl/fl); B6.129S1-Relafl/fl (Relafl/fl); B6.Cg-Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/J (Rosa26TdTomato fl/+); and B6.129S4-Socs3tm1Ayos/J (Socs3fl/fl). B6.Cg-Tg(Cd4-Cre)1Cwi (Cd4-Cre) were purchased from Taconic and B6.CD45.1 from Frederick Cancer Center. All strains were on a B6 background. All intercrosses to generate additional strains like WT and IL-1R-deficient dual reporter mice (Il17fthy1.1.Foxp3gfp), Il17fthy1.1.CD45.1/CD45.2 and Stat5bfl/fl. Cd4-Cre mice were generated by crosses in our breeding facility. Animals were bred and maintained under specific pathogen-free condition in accordance with institutional animal care and use committee regulations.
Basu R., Whitley S.K., Bhaumik S., Zindl C.L., Schoeb T.R., Benveniste E.N., Pear W.S., Hatton R.D, & Weaver C.T. (2015). IL-1 signaling modulates STAT activation to antagonize retinoic acid signaling and control Th17–iTreg balance. Nature immunology, 16(3), 286-295.
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