Microcat 2 spect ct

Tumors developed to 8–15 mm in diameter after 3–4 weeks of inoculation in the mice. Agents (2–10 nanomols) were injected into the tail veins of anesthetized mice. Mice were imaged immediately after injection and for as long as 48 h afterward. Optical and x-ray images were recorded by Kodak In-Vivo Multispectral System FX (Carestream Health Molecular Imaging, New Haven, CT). In vivo positron emission tomography (PET)/single photon emission computed tomography (SPECT)/computed tomography (CT) imaging was performed on a Siemens MicroCAT II SPECT/CT and Inveon PET instruments (Siemens Medical Solutions, Malvern, PA).

Tumors developed after 3 to 4 weeks of growth in the implanted mice to 8–15 mm in diameter. Imaging agents (2–10 nM) were injected into the tail vein of anesthetized mice. Mice were imaged immediately after injection and for as long as 72 hours subsequently. Optical and X-ray images were recorded using the Bruker In-Vivo Multispectral System FX Pro instrument (Bruker Preclinical Imaging, Billerica, MA). In vivo PET/single-photon emission CT (SPECT)/CT imaging was performed using the Siemens MicroCAT II SPECT/CT and Inveon PET instrument (Siemens Medical Solutions, Malvern, PA).