Ferric chloride hexahydrate fecl3 6h2o

The standard diclofenac sodium powder obtained from the National Organization for Drug Control and Research (NODCAR, Egypt) was used as template for the synthesis of the MMIP. Aniline (Al-Alamia for Chemical Industries, Egypt), and ammonium persulfate (APS) were used for the synthesis of the molecularly imprinted polyaniline. Ferric chloride hexahydrate (FeCl₃·6H₂O, Daejung Chemicals and Metals, South Korea), ethylene glycol (Honeywell International Inc., USA), and anhydrous sodium acetate (ADWIC, Egypt) were used in the solvothermal synthesis of SPIONs. Absolute ethyl alcohol was purchased from the international Company for Medical Industries, Egypt. Methyl alcohol, hydrochloric acid and glacial acetic acid used throughout the experimental work are ADWIC products (Egypt). Double distilled water was used for the preparation of all aqueous solutions. All reagents were analytical grade and used without any further purification.

Chlorpyrifos, a product of Excel Crop Care Limited, was provided by El Nasr for Intermediate Chemicals (Egypt) and was used as a template. For the synthesis of the molecularly imprinted polyaniline, aniline (Al-Alamia for Chemical Industries, Egypt), dimethyl sulphoxide (Oxford Lab Fine Chem LLP, India) and ammonium persulphate (APS, Veb-Laborchemie Apolda, Germany) were used. Ethylene glycol (Honeywell International Inc., USA), ferric chloride hexahydrate (FeCl₃·6H₂O, Daejung Chemicals and Metals, South Korea) and anhydrous sodium acetate (ADWIC, Egypt) were utilized in the solvothermal synthesis of SPIONs. Ethyl alcohol was obtained from the International Company for Medical Industries (Egypt), methyl alcohol and hydrochloric acid were purchased from Alpha Chemika (India), and glacial acetic acid was provided by Piochem (Egypt). All reagents were of analytical grade and were used without any further purification.

Bromophenol blue was obtained from Carlo Erba Reagents (Barcelona, Spain). For the synthesis of the AD, tert-butyl-[2-(3,5-dihydroxyphenyl)-2-hydroxyethyl]azanium sulphate (TBDA sulphate, molar mass 548.65 g mol⁻¹, Borg Pharmaceutical Industries, Borg El-Arab, Alexandria, Egypt), aniline (Al-Alamia for Chemical Industries, Egypt), sodium carbonate (ADWIC, Egypt) and sodium nitrite (SDFCL, India) were used. Ferric chloride hexahydrate, FeCl₃·6H₂O (Daejung Chemicals and Metals, South Korea), anhydrous sodium acetate (ADWIC, Egypt) and ethylene glycol (Honeywell International Inc., USA) were used to synthesize the SPIONs. Hydrochloric acid was purchased from Alpha Chemika (India) and ethyl alcohol was obtained from the International Company for Medical Industries (Egypt). All chemical reagents were of analytical grade and were used as received without any further purification. A BPB stock solution (1000 mg L⁻¹) was prepared by dissolving 50 mg of BPB in 50 mL of double distilled water. Working BPB solutions (10–100 mg L⁻¹) were prepared by diluting a stock BPB solution (1000 mg L⁻¹) with distilled water shortly before each experiment.