Magnetom scanner

Manufactured by Siemens

Sourced in Germany, United States

The Magnetom scanner is a medical imaging device manufactured by Siemens. It uses powerful magnetic fields and radio waves to generate detailed images of the human body. The Magnetom scanner allows healthcare professionals to diagnose and monitor various medical conditions.

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Lab products found in correlation

56 protocols using magnetom scanner

7T fMRI Protocol for Motivation Studies

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This study was carried out on a 7 Tesla (T) MAGNETOM scanner (Siemens Healthcare, Erlangen, Germany) using 32-channel head coil at the Auburn University MRI Research Center in Auburn, AL, USA. Prior studies have shown higher functional specificity using 7T vs. 3T in terms of percent signal change, mean t-values, number of supra-threshold voxels, and contrast to noise ratio (Beisteiner et al., 2011 (link); Geißler et al., 2014 (link)). Thus, compared to using the same number of subjects at 3T, the likelihood of detecting true activations is better at 7T. Functional brain imaging data were acquired using a multiband echo-planar imaging sequence (Feinberg et al., 2010 (link)) with repetition time (TR) = 1-s, echo time (TE) = 20-ms, slice thickness = 2 mm, gap between slices = 3 mm, flip angle = 70°, in-plane resolution of 2 × 2 mm², and multi-band factor of 2. Also, a high-resolution 3D MPRAGE sequence was used to collect T1-weighted structural data for anatomical localization for the fMRI data. Visual stimuli were presented to participants in three different runs per session, with each run lasting approximately 16 min. Runs were randomized for each participant, but were counterbalanced to consist of 42 trials with 14 trials for each of the three motivations, selected without replacement.

Goodman A.M., Wang Y., Kwon W.S., Byun S.E., Katz J.S, & Deshpande G. (2017). Neural Correlates of Consumer Buying Motivations: A 7T functional Magnetic Resonance Imaging (fMRI) Study. Frontiers in Neuroscience, 11, 512.

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Standardized Multimodal MRI Protocol

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MRI scanning was performed on a 1.5T Magnetom scanner (Siemens, Erlangen, Germany). The scanning protocol included whole-brain 3D T1 magnetization-prepared rapid gradient echo sequence (repetition time [TR]/echo time [TE]/inversion time [TI] 2,730/2.95/1,000 ms; flip angle 7°; voxel size 1.0 × 1.0 × 1.0 mm); fluid-attenuated inversion recovery (FLAIR) pulse sequences (TR/TE/TI 12,220/85/2,200 ms; voxel size 1.0 × 1.2 × 3.0; slice gap 0.6 mm); transversal T2-weigted turbo spin echo sequence (TR/TE 7,440/96 ms; voxel size 0.9/0.9 × 3.0 mm; slice gap 0.6 mm); and gradient echo susceptibility-weighted imaging (SWI) sequence (TR/TE 49/40 ms; voxel size 0.8 × 0.7 × 1.0 mm). All patients underwent MRI scanning according to this standardized protocol.^{8 (link)}

Arntz R.M., van den Broek S.M., van Uden I.W., Ghafoorian M., Platel B., Rutten-Jacobs L.C., Maaijwee N.A., Schaapsmeerders P., Schoonderwaldt H.C., van Dijk E.J, & de Leeuw F.E. (2016). Accelerated development of cerebral small vessel disease in young stroke patients. Neurology, 87(12), 1212-1219.

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Acquisition of T1-weighted Anatomical Images

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T1-weighted anatomical images were obtained for DS1-DS7 using an MPRAGE (Mugler and Brookeman, 1991 (link)) sequence (192 slices; TR=1900 ms; FOV: 256×256 mm; flip angle= 9°; TE= 2.52 ms; spatial resolution 0.8 mm isotropic voxels) which were col- lected with a 3T Siemens Magnetom Prisma^fit system. The anatomical images for DS8 were acquired using a MP2RAGE (Marques et al., 2010 (link)) sequence (192 slices; TR=4300 ms; FOV: 240×225 mm; flip angle= 4°; TE= 2.27 ms; spatial resolution 0.8 mm isotropic voxels) collected with a 7T Siemens Magnetom scanner. Anatomical images were used only to visualize data and define regions of interest (ROIs, see Region of Interest Creation, below).

Dowdle L.T., Vizioli L., Moeller S., Akçakaya M., Olman C., Ghose G., Yacoub E, & Uğurbil K. (2023). Evaluating increases in sensitivity from NORDIC for diverse fMRI acquisition strategies. NeuroImage, 270, 119949.

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Functional Neuroimaging with 3T MRI

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Participants were scanned using a 3 T Siemens Magnetom scanner. A total of 166 functional images per run were taken with a gradient echo planar imaging (EPI) sequence (repetition time = 2900 ms; echo time = 27 ms; 64 × 64 matrix; 90° flip angle; 22 cm field of view). Whole-brain coverage was obtained with 44 axial slices (thickness, 2.5 mm. 5 mm spacing; in-plane resolution, 3.44 × 3.44 mm). A high-resolution anatomical scan (3-dimensional spoiled gradient recalled acquisition in a steady state; repetition time = 2530 ms; echo time = 3.03 ms; 25.6 cm field of view; 7° flip angle; 176 axial slices; thickness, 1.0 mm; 256 × 256 matrix) in register with the EPI dataset was obtained covering the whole brain.

White S.F., Costanzo M.E., Blair J.R, & Roy M.J. (2014). PTSD symptom severity is associated with increased recruitment of top-down attentional control in a trauma-exposed sample. NeuroImage : Clinical, 7, 19-27.

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High-resolution Functional Imaging at 7T

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All measurements were performed on a 7T Siemens Magnetom scanner equipped with a body gradient system (70 mT/m maximum amplitude, 200 mT/m/s maximum slew rate) and a dedicated surface coil (16-channel receive and a separate four channel transmit coil with a pre-determined static B1 phase set optimized for homogeneity over the visual cortex; Live Services, Minneapolis, MN, USA) covering the posterior part of the subjects' heads. Compared to a whole brain coil, this RF coil offers better transmit efficiency (reduced SAR) in occipital areas and a wide angle for visual stimulation. Three subjects [two females, age (28.3 ± 1.5) years] were scanned for imaging PSF and functional measurements. Three additional male subjects (age 33.3 ± 3.5) were scanned for the PSF measurements only (see below). All subjects were scanned after giving informed written consent and in compliance with the local ethical board.

Kemper V.G., De Martino F., Vu A.T., Poser B.A., Feinberg D.A., Goebel R, & Yacoub E. (2015). Sub-millimeter T2 weighted fMRI at 7 T: comparison of 3D-GRASE and 2D SE-EPI. Frontiers in Neuroscience, 9, 163.

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Resting-State fMRI Protocols at 3T and 7T

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The 3T resting-state fMRI protocol for the CamCAN dataset included an echo planar imaging (EPI) sequence (TR=1970 ms; TE=30 ms; FOV: 192×192 mm; 3×3×4.4 mm³ voxel resolution; duration: 8.5 minutes); data was collected at a single site using a 3T Siemens TIM Trio scanner with a 32-channel head coil (24 (link)). Participants were asked to lie motionless with their eyes closed and not fall asleep during the scan.
The acquisition protocol for the HCP 7T resting-state fMRI data included a multiband gradient-echo EPI sequence (TR=1000 ms; TE=22.2 ms; FOV: 208×208 mm; 1.6 mm isotropic voxel resolution; duration: 16 minutes); data was collected at a single site using a 7T Siemens Magnetom scanner (25 (link)). During the acquisition, participants were asked to keep their eyes open and fixate on a cross, shown on a presentation screen inside the scanner.

Veréb D., Mijalkov M., Canal-Garcia A., Chang Y.W., Gomez-Ruis E., Gerboles B.Z., Kivipelto M., Svenningsson P., Zetterberg H., Volpe G., Betts M.J., Jacobs H, & Pereira J.B. (2023). Age-related differences in the functional topography of the locus coeruleus: implications for cognitive and affective functions. medRxiv.

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Hippocampal Volume Assessment via MRI

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Structural MRI data were acquired at the MNI for all participants on a 3 T Siemens Magnetom scanner using a standard head coil. Hippocampal volume was assessed using FreeSurfer version 6.0 using the Desikian–Killiany–Touriner atlas gray matter segmentation. Hippocampal volume was adjusted for intracranial volume.

Therriault J., Pascoal T.A., Lussier F.Z., Tissot C., Chamoun M., Bezgin G., Servaes S., Benedet A.L., Ashton N.J., Karikari T.K., Lantero-Rodriguez J., Kunach P., Wang Y.T., Fernandez-Arias J., Massarweh G., Vitali P., Soucy J.P., Saha-Chaudhuri P., Blennow K., Zetterberg H., Gauthier S, & Rosa-Neto P. (2022). Biomarker modeling of Alzheimer’s disease using PET-based Braak staging. Nature Aging, 2(6), 526-535.

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Structural Brain Imaging with MRI

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All subjects underwent an anatomical MRI examination performed on a 1.5-T Magnetom scanner (Siemens), including a 3-D anatomic T1-weighted sequence covering the whole brain volume, with 1-mm³ cubic voxels and 176 1-mm thick slices (TR = 1970 ms, TE = 3.93 ms). This scan was done before PET scan to control subject anatomy, electrode position and was further used for spatial normalization and to define the regions of interest (ROI).

Fonteneau C., Redoute J., Haesebaert F., Le Bars D., Costes N., Suaud-Chagny M.F, & Brunelin J. (2018). Frontal Transcranial Direct Current Stimulation Induces Dopamine Release in the Ventral Striatum in Human. Cerebral Cortex (New York, NY), 28(7), 2636-2646.

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High-Field fMRI Acquisition and Safety Monitoring

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Data was acquired on a 7-Tesla Siemens Magnetom scanner with a 32-receive channel head coil (8-channel parallel transmit). Anatomical T1-weighted scan was acquired at the beginning of the first scanning session, using a magnetization-prepared rapid gradient echo sequence (MPRAGE) with voxel size of 0.75 × 0.75×0.75 mm isotropic (field of view = 208×157 x 110 mm [A-P; R-L; F-H], encoding direction coronal). Functional data were acquired using a sequence (GRAPPA 3, multi-band acceleration factor 2, repetition time [TR]=1.0 s, echo time [TE]=20 ms, flip angle [FA]=30 deg). We acquired 44 slices with isotropic voxel size of 2 × 2 × 2 mm. For estimating magnetic field inhomogeneities, we additionally acquired a gradient echo field map. Acquisition was in the transversal orientation with field of view 210 × 210 × 160 mm and 64 slices with 2.5 mm thickness (TR = 475 ms, TE = 4.08 ms, FA = 35 deg). To monitor the use of 7T for human research, participants filled out a questionnaire rating their levels of dizziness, wellbeing, alertness and focus after each imaging session.

Berlot E., Popp N.J, & Diedrichsen J. (2020). A critical re-evaluation of fMRI signatures of motor sequence learning. eLife, 9, e55241.

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High-Field MRI Acquisition Protocol

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MRI was performed with a 7 T Siemens Magnetom scanner, with 70 mT/m gradient strength and a 32 channel Rx, single channel birdcage Tx head coil (Nova Medical).

Faull O.K, & Pattinson K.T. (2017). The cortical connectivity of the periaqueductal gray and the conditioned response to the threat of breathlessness. eLife, 6, e21749.

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