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Pluronic 188

Manufactured by Merck Group
Sourced in India, United States

Pluronic 188 is a non-ionic block copolymer surfactant produced by BASF, a subsidiary of Merck Group. It is commonly used as a wetting agent, emulsifier, and dispersing agent in various applications, including pharmaceutical, cosmetic, and industrial formulations.

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2 protocols using pluronic 188

1

Formulation and Characterization of PLGA Nanoparticles

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PLGA (75:25), DSF and Pluronic 188® was purchased from Sigma Aldrich® (Bangalore, India). Polysorbate 80 and Triton X 100® were purchased from Himedia® (Mumbai, India). All other chemicals used were of analytical grade.
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2

Skin Penetration Enhancement with Pluronic F-188 and Chitosan

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PLURONIC 188, CHT of medium molecular weight (190–310 kDa) with 75–85% deacetylation degree from crab shells, PCT from citrus fruits, mucin from porcine stomach (type II, bound sialic acid ∼ 1%), Schiff’s reagent 1% basic fuchsine, periodic acid, and sodium metabisulfite were supplied by Sigma (St Louis, MO, USA). LDC and PLC were gifted by Cristália Prod. Quim. Farm. Ltda (Itapira, Brazil). EMLA cream was purchased by AstraZeneca (Brazil). Cetyl palmitate (CP) was donated by Dhaymers Química Fina (Taboao Da Serra, Brazil) and capric/caprylic triglycerides were provided from Lipo do Brasil Ltda (São Bernardo do Campo, Brazil). High-performance liquid chromatography (HPLC)-grade acetonitrile was from J.T. Baker, Phillipsburg, NJ, USA. Deionized water (18 MΩ) was achieved from an Elga USF Maxima Ultra-Pure water purifier (Elga LabWater, High Wycombe, UK).
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