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Spectris mr injection system

Manufactured by Bayer
Sourced in United States

The Spectris MR Injection System is a laboratory equipment designed for precise and controlled injection of samples. The system provides accurate and repeatable injections for various analytical applications.

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5 protocols using spectris mr injection system

1

MRI Protocol for Stroke Diagnosis

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Magnetic resonance imaging was performed on a 1.5-T MR system (Magnetom Avanto or Sonata, Siemens Medical Systems, Erlangen, Germany) at admission. A standardized protocol was used in all patients including (1) transverse, coronal and sagittal localizing sequences followed by transverse oblique contiguous images aligned with the inferior borders of the corpus callosum (applied on sequences 2–5 and 7); (2) T1-weighted spin echo sequence; (3) T2-weighted turbo spin echo sequence; (4) isotropic diffusion-weighted echo-planar spin-echo sequence (DWI); (5) fluid attenuated inversion recovery (FLAIR) sequence; (6) a time-of-flight MRA; and (7) PWI following the first pass of contrast bolus through the brain. Perfusion-weighted imaging was acquired using a gradient-echo echo planar imaging sequence. The contrast agent gadoteric acid (Dotarem, Guerbet, Aulnay-sous-Bois, France) was bolus injected by a power injector (Spectris MR injection system, Medrad, Volkach, Germany) with a dose of 0.1 mmol/kg of body weight at a rate of 4 ml/sec.
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2

Endorectal MRI Imaging Protocol

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All MR imaging studies were performed using a combination of an endorectal coil (BPX-30; Medrad, Pittsburgh, PA, USA) tuned to 127.8 MHz and a 16-channel cardiac coil (SENSE; Philips Medical Systems, Best, the Netherlands) with a 3T magnet (Achieva: Philips Medical Systems, Best, the Netherlands), without prior bowel preparation. The endorectal coil was inserted using a semi-anesthetic gel (xylocaine, Lidocaine, Astra-Zeneca, Wilmington, DE, USA) while the patient was in the left lateral decubitus position. The balloon surrounding the coil was distended with 3-mol/L perfluorocarbon (Fluorinert; 3M, St Paul, MN, USA) to a volume of approximately 45mL, to reduce susceptibility artefacts induced by air in the coil’s balloon. The MR imaging protocol included triplanar T2-weighted turbo spin echo imaging, DW MRI imaging, axial three-dimensional fast-field-echo DCE MRI. Axial DCE images were obtained before, during, and after a single- dose of gadopentetate dimeglumine (Magnevist; Berlex, Wayne, NJ, USA), administered at a dose of 0.1 mmol per kilogram of body weight through a peripheral vein at a rate 3 mL/sec using a mechanical injector (Spectris MR injection System; Medrad, Pittsburgh, PA, USA). Sequence parameters were defined in previous studies [16 (link), 17 (link)].
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3

Dynamic Contrast-Enhanced MRI Protocol

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All patients underwent a 3.0-T MR examination (MR 750, GE Medical Systems, Waukesha, WI, USA, and Achieva, Philips, the Netherlands). The general sequences consisted of T2-weighted imaging (T2WI), precontrast T1-weighted imaging (T1WI), and the arterial phase and portal-venous phase of dynamic contrast-enhanced MRI (DCE-MRI). For the DCE-MRI sequence, 20 mL of gadopentetate dimeglumine (Magnevist; Schering, Guangzhou, China) was administered intravenously with a pressure injector (Spectris MR Injection System, MEDRAD, Inc., USA) at 2–3 mL/s, followed by a 20-mL saline solution flush. The scanning times were set to 30 s and 60 s after the contrast agent was injected to obtain the arterial phase and portal-venous phase images, respectively. Detailed information on the acquisition parameters is described in Table 1.
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4

Contrast-Enhanced 3D-LAVA Liver MRI

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Participants in our study were examined on a 3.0 T whole body MR scanner (Signa; GE Medical Systems, Milwaukee, WI). When the respiratory signals were established, the patient was positioned supinely in an 8-channel phased array body coil. The routine MR sequences included SPGR T1-weighted imaging (T1WI), and fast recovery fast spin echo (FRFSE) T2-weighted imaging (T2WI). Subsequently, 10-mL gadodiamide (Magnevist; Bayer Healthcare, Germany) was intravenously injected via a pressure injector (Spectris MR Injection System; Medrad, Warrendale, PA) at a dose of 3 mL/s for a total of 0.2 mmol per kg of body weight followed by a 20-mL saline solution flush for axial contrast-enhanced three-dimensional liver acquisition with volume acceleration (3D-LAVA). The parameters for the axial 3D LAVA were as follows: TR = 3.9 ms, TE = 1.8 ms, field of view = 34×34 cm, slice thickness = 5.0 mm, and matrix of 256×224 mm. The scanning coverage was from the diaphragm to the inferior border of the spleen to cover the entire liver and spleen.
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5

Multiparametric MRI Prostate Imaging Protocol

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All imaging studies were performed with a combination of an endorectal coil (BPX-15; Medrad, Pittsburgh, PA) tuned to 127.8 MHz and a sixteen-channel cardiac coil with a parallel imaging (sensitivity-encoding [SENSE]; Philips Medical Systems, Best, the Netherlands) technique with a 3T MR scanner (Achieva; Philips Medical Systems). The endorectal coil was filled with 45 mL of Galden Perfluorinated Fluid (Solvay Specialty Polymers, Milan, Italy). MR imaging parameters included T1-weighted imaging, triplanar (coronal, sagittal, and axial) T2-weighted (T2W) turbo-spin-echo, apparent diffusion coefficient maps, high b-value diffusion weighted image (DWI) (b2000 sec/mm2) and dynamic contrast enhanced (DCE) MRI sequences. Axial DCE images were obtained before, during, and after a single dose of gadopentetate dimeglumine (Magnevist; Berlex, Wayne, NJ) or gadoterate meglumine (Dotarem, Guerbet, Bloomington, IN) administered at a dose of 0.1 mmol/kg of body weight through a peripheral vein at a rate of 3 mL/sec by using a mechanical injector (Spectris MR Injection System; Medrad, Pittsburgh, PA). MR imaging pulse sequence parameters are defined in Table 1.
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