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Anti human psen2 ctf ep1515y

Manufactured by Abcam
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Anti-human PSEN2-CTF (EP1515Y) is a recombinant rabbit monoclonal antibody that recognizes the C-terminal fragment of human Presenilin-2 (PSEN2). This antibody is suitable for use in various applications such as Western blotting, immunohistochemistry, and immunocytochemistry.

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Lab products found in correlation

Anti human psen1 ctf mab5232, by Merck Group (2 mentions) Anti human psen1 ntf mab1563, by Merck Group (2 mentions) Horseradish peroxidase conjugated anti mouse, by Bio-Rad (2 mentions) Anti rat igg, by Thermo Fisher Scientific (2 mentions) Elisa kit, by Tecan (2 mentions) Anti rabbit igg, by Bio-Rad (2 mentions)

2 protocols using anti human psen2 ctf ep1515y

1

Antibody Characterization for Alzheimer's Biomarkers

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The following antibodies were used in western blot analysis: anti-human PSEN1-CTF (MAB5232) and anti-human PSEN1-NTF (MAB1563) purchased from Merck Millipore; anti-human PSEN2-CTF (EP1515Y) purchased from Abcam; rabbit anti-PEN2 (B126) and mouse anti-NCSTN (9C3) kindly provided by Prof. Wim Annaert. Horse radish peroxidase (HRP)-conjugated anti-mouse (#1721011) and anti-rabbit IgG (#1721019) purchased from Bio-Rad and anti-rat IgG (#61-9520) purchased from Thermo Fisher. Antibodies used in the MesoScale Discovery (MSD) multispot Aβ ELISA were obtained through collaboration with Janssen Pharmaceutica NV (Beerse, Belgium). The MSD ELISA capture antibodies were JRD/Aβ37/3 for Aβ37, JRF AB038 for Aβ38, JRF/cAb40/28 for Aβ40, JRF/cAb42/26 for Aβ42, and the detection antibody was JRF/AbN/25 raised against the N terminus of Aβ. The antibodies used in the Aβ43 ELISA were anti-Aβ43 rabbit IgG (capture antibody) and anti-Aβ (N) (82E1) mouse IgG Fab’ (detection antibody), both supplied with the ELISA kit (IBL).
Petit D., Fernández S.G., Zoltowska K.M., Enzlein T., Ryan N.S., O’Connor A., Szaruga M., Hill E., Vandenberghe R., Fox N.C, & Chávez-Gutiérrez L. (2022). Aβ profiles generated by Alzheimer’s disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset. Molecular Psychiatry, 27(6), 2821-2832.
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2

Western Blot Analysis of Alzheimer's Proteins

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The following antibodies were used in western blot analysis: anti-human PSEN1-CTF (MAB5232) and anti-human PSEN1-NTF (MAB1563) purchased from Merck Millipore; anti-human PSEN2-CTF (EP1515Y) purchased from Abcam; rabbit anti-PEN2 (B126) and mouse anti-NCSTN (9C3) kindly provided by Prof. Wim Annaert. Horse radish peroxidase (HRP)-conjugated anti-mouse (#1721011) and anti-rabbit IgG (#1721019) purchased from Bio-Rad and anti-rat IgG (#61-9520) purchased from Thermo Fisher. Antibodies used in the MesoScale Discovery (MSD) multispot Aβ ELISA were obtained through collaboration with Janssen Pharmaceutica NV (Beerse, Belgium). The MSD ELISA capture antibodies were JRD/Aβ37/3 for Aβ37, JRF AB038 for Aβ38, JRF/cAb40/28 for Aβ40, JRF/cAb42/26 for Aβ42, and the detection antibody was JRF/AbN/25 raised against the N terminus of Aβ. The antibodies used in the Aβ43 ELISA were anti-Aβ43 rabbit IgG (capture antibody) and anti-Aβ (N) (82E1) mouse IgG Fab’ (detection antibody), both supplied with the ELISA kit (IBL).
Petit D., Fernández S.G., Zoltowska K.M., Enzlein T., Ryan N.S., O’Connor A., Szaruga M., Hill E., Vandenberghe R., Fox N.C, & Chávez-Gutiérrez L. (2022). Aβ profiles generated by Alzheimer’s disease causing PSEN1 variants determine the pathogenicity of the mutation and predict age at disease onset. Molecular Psychiatry, 27(6), 2821-2832.
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