Mylab8

US and fusion imaging CEUS examinations were performed using ultrasound systems (Esaote MyLab Class C, Esaote MyLab Twice, Esaote MyLab8) equipped with a two-dimensional convex array probe (CA541, C1-8) with a probe frequency ranging from 1 to 8 MHz. The image fusion system was configured and equipped with software for CEUS imaging technology. A low mechanical index (MI) parameter technique (CnTI imaging technique) was used, and the mechanical index was maintained below 0.20 to reduce the destruction of microbubbles.

All cerebrovascular hemodynamic indices were evaluated by an experienced neurologist blinded for the clinical and biological data of the patients and healthy controls by an ultrasound machine with high resolution (Esaote MyLab 8, Genoa, Italy), equipped with a Color Ultrasound System, which included two transducers: one with a selectable minimum frequency band between 1.7 MHz and 4 MHz (multifrequency sectorial transducer-phased array) and another probe with a frequency from 3.6 MHz to 16 MHz (linear transducer). The cerebrovascular ultrasound technique was applied as presented previously [34 (link)]. Briefly, we will describe the methods utilized.