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Laser based hematologic analyzer

Manufactured by Beckman Coulter
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The Laser based hematologic analyzer is a laboratory instrument designed to analyze and quantify various blood components, including red blood cells, white blood cells, and platelets. The core function of this analyzer is to utilize laser technology to detect and measure the properties of these blood cells, providing detailed information about the patient's hematological profile.

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Lab products found in correlation

Biochemistry panel plus analyzer discs, by Abaxis (19 mentions) Piccolo point of care analyzer, by Abaxis (13 mentions) Point of care analyzer, by Abaxis (7 mentions) Sta neoplastine ci plus, by Diagnostica Stago (4 mentions) Fibri prest automate, by Diagnostica Stago (4 mentions) Ptt automate, by Diagnostica Stago (4 mentions) Sta thrombin, by Diagnostica Stago (2 mentions)

20 protocols using laser based hematologic analyzer

1

Comprehensive Hematologic and Biochemical Analysis

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EDTA-treated blood was analyzed using a laser-based hematologic analyzer (Beckman Coulter) to determine total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations. A Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis) were used to test for serum concentrations of albumin, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, cholesterol, total protein, blood urea nitrogen (BUN), creatinine (CRE), uric acid, and C-reactive protein (CRP).
Woolsey C., Jankeel A., Matassov D., Geisbert J.B., Agans K.N., Borisevich V., Cross R.W., Deer D.J., Fenton K.A., Latham T.E., Gerardi C.S., Mire C.E., Eldridge J.H., Messaoudi I, & Geisbert T.W. (2020). Immune correlates of postexposure vaccine protection against Marburg virus. Scientific Reports, 10, 3071.
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2

Comprehensive Blood Profiling Protocol

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Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), blood urea nitrogen (BUN), calcium, creatinine (CRE), C-reactive protein (CRP), gamma-glutamyltransferase (GGT), glucose, total protein, and uric acid by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis).
Cross R.W., Prasad A.N., Borisevich V., Geisbert J.B., Agans K.N., Deer D.J., Fenton K.A, & Geisbert T.W. (2020). Crimean-Congo hemorrhagic fever virus strains Hoti and Afghanistan cause viremia and mild clinical disease in cynomolgus monkeys. PLoS Neglected Tropical Diseases, 14(8), e0008637.
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3

Comprehensive Blood Profiling Protocol

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Total white blood cell counts, white blood cell differentials, red
blood cell counts, platelet counts, hematocrit values, total hemoglobin
concentrations, mean cell volumes, mean corpuscular volumes, and mean
corpuscular hemoglobin concentrations were analyzed from blood collected in
tubes containing EDTA using a laser based hematologic analyzer (Beckman
Coulter). Serum samples were tested for concentrations of albumin, amylase,
alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline
phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, calcium, uric
acid, total protein, blood urea nitrogen (BUN), creatinine (CRE), and
C-reactive protein (CRP) by using a Piccolo point-of-care analyzer and
Biochemistry Panel Plus analyzer discs (Abaxis).
Bornholdt Z.A., Herbert A.S., Mire C.E., He S., Cross R.W., Wec A.Z., Abelson D.M., Geisbert J.B., James R.M., Rahim M.N., Zhu W., Borisevich V., Banadyga L., Gunn B.M., Agans K.N., Wirchnianski A.S., Goodwin E., Tierney K., Shestowsky W.S., Bohorov O., Bohorova N., Velasco J., Ailor E., Kim D., Pauly M.H., Whaley K.J., Alter G., Walker L.M., Chandran K., Zeitlin L., Qiu X., Geisbert T.W, & Dye J.M. (2019). A two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates. Cell host & microbe, 25(1), 49-58.e5.
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4

Comprehensive Blood Analysis Protocol

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Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser based hematologic analyzer (Beckman Coulter). A Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis) were used to test for serum concentrations of albumin, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, cholesterol, total protein, blood urea nitrogen (BUN), creatinine (CRE), uric acid, and C-reactive protein (CRP).
Woolsey C., Menicucci A.R., Cross R.W., Luthra P., Agans K.N., Borisevich V., Geisbert J.B., Mire C.E., Fenton K.A., Jankeel A., Anand S., Ebihara H., Geisbert T.W., Messaoudi I, & Basler C.F. (2019). A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge. Cell reports, 28(12), 3032-3046.e6.
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5

Comprehensive Hematological and Biochemical Analyses

Check if the same lab product or an alternative is used in the 5 most similar protocols
Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, cholesterol, total protein, total bilirubin (TBIL), blood urea nitrogen (BUN), creatinine (CRE), and C-reactive protein (CRP) by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis). Citrated plasma samples were analyzed for coagulation parameters prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen on the STart4 instrument using the PTT Automate, STA Neoplastine CI plus, and Fibri-Prest Automate, kits, respectively (Diagnostica Stago).
Thi E.P., Mire C.E., Lee A.C., Geisbert J.B., Zhou J.Z., Agans K.N., Snead N.M., Deer D.J., Barnard T.R., Fenton K.A., MacLachlan I, & Geisbert T.W. (2015). Lipid nanoparticle siRNA treatment of Ebola virus Makona infected nonhuman primates. Nature, 521(7552), 362-365.
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6

Comprehensive Hematological and Biochemical Analyses

Check if the same lab product or an alternative is used in the 5 most similar protocols
Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, cholesterol, total protein, total bilirubin (TBIL), blood urea nitrogen (BUN), creatinine (CRE), and C-reactive protein (CRP) by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis). Citrated plasma samples were analyzed for coagulation parameters prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen on the STart4 instrument using the PTT Automate, STA Neoplastine CI plus, and Fibri-Prest Automate, kits, respectively (Diagnostica Stago).
Thi E.P., Mire C.E., Lee A.C., Geisbert J.B., Zhou J.Z., Agans K.N., Snead N.M., Deer D.J., Barnard T.R., Fenton K.A., MacLachlan I, & Geisbert T.W. (2015). Lipid nanoparticle siRNA treatment of Ebola virus Makona infected nonhuman primates. Nature, 521(7552), 362-365.
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7

Comprehensive Hematological and Biochemical Analysis

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Hematological analysis including total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, alanine aminotransferase (ALT) aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), glucose, cholesterol, total protein, total bilirubin (TBIL), blood urea nitrogen (BUN), creatinine (CRE), and C-reactive protein (CRP) by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis).
Mire C.E., Satterfield B.A., Geisbert J.B., Agans K.N., Borisevich V., Yan L., Chan Y.P., Cross R.W., Fenton K.A., Broder C.C, & Geisbert T.W. (2016). Pathogenic Differences between Nipah Virus Bangladesh and Malaysia Strains in Primates: Implications for Antibody Therapy. Scientific Reports, 6, 30916.
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8

Comprehensive Blood Analysis Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser-based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, ALT, AST, ALP, GGT, glucose, cholesterol, total protein, total bilirubin, BUN, CRE, and CRP by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis). Citrated plasma samples were analyzed for coagulation parameters PT, APTT, thrombin time, and fibrinogen on the STart4 instrument using the PTT Automate, STA Neoplastine CI Plus, STA Thrombin, and Fibri-Prest Automate kits, respectively (Diagnostica Stago). Citrated plasma levels of D-dimers were measured by enzyme-linked immunosorbent assay according to the manufacturer's recommendations (Diagnostica Stago).
Thi E.P., Mire C.E., Ursic-Bedoya R., Geisbert J.B., Lee A.C., Agans K.N., Robbins M., Deer D.J., Fenton K.A., MacLachlan I, & Geisbert T.W. (2014). Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA. Science translational medicine, 6(250), 250ra116.
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9

Comprehensive Blood Profile Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols
Total white blood cell counts, white blood cell differential counts, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser-based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of albumin, amylase, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ-glutamyltransferase, glucose, cholesterol, total protein, total bilirubin, blood urea nitrogen, creatinine, and C-reactive protein by using a Piccolo point-of-care analyzer and BioChemistry Panel Plus analyzer discs (Abaxis).
Mire C.E., Geisbert J.B., Borisevich V., Fenton K.A., Agans K.N., Flyak A.I., Deer D.J., Steinkellner H., Bohorov O., Bohorova N., Goodman C., Hiatt A., Kim D.H., Pauly M.H., Velasco J., Whaley K.J., Crowe JE J.r., Zeitlin L, & Geisbert T.W. (2017). Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Science translational medicine, 9(384), eaai8711.
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10

Comprehensive Blood Biomarker Analysis

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Total white blood cell counts, white blood cell differentials, red blood cell counts, platelet counts, hematocrit values, total hemoglobin concentrations, mean cell volumes, mean corpuscular volumes, and mean corpuscular hemoglobin concentrations were analyzed from blood collected in tubes containing EDTA using a laser-based hematologic analyzer (Beckman Coulter). Serum samples were tested for concentrations of alanine aminotransferase (ALT), albumin, alkaline phosphatase (ALP), amylase, aspartate aminotransferase (AST), C-reactive protein (CRP), calcium, creatinine, gammaglutamyltransferase (GGT), glucose, total protein, blood urea nitrogen (BUN), and uric acid, and by using a Piccolo point-of-care analyzer and Biochemistry Panel Plus analyzer discs (Abaxis).
Cross R.W., Bornholdt Z.A., Prasad A.N., Geisbert J.B., Borisevich V., Agans K.N., Deer D.J., Melody K., Fenton K.A., Feldmann H., Sprecher A., Zeitlin L, & Geisbert T.W. (2020). Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment. Nature Communications, 11, 3736.
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