11kdht

11KT, 11KDHT and mibolerone (Mib) were purchased from Steraloids. T and DHT were purchased from Sigma-Aldrich, while [H³]-Mib (76.8 Ci/mmol) was purchased from Perkin Elmer. All steroids were dissolved in absolute ethanol and added to the culturing medium at a final concentration of no more than 0.1% ethanol. Cortisol-9, 11, 12, 12-d4 (cortisol-d9), testosterone-1, 2-d2 (T-d2), progesterone-2, 2, 4, 6, 6, 17α, 21, 21, 21-d9 (P4-d9) and 4-pregnen-17α-ol-3,20-dione-2, 2, 4, 6, 6, 21, 21, 21-d8 (17OHP4-d8) were purchased from Cambridge Isotope Laboratories. Gestodene (GES) and drospirenone (DRSP) were purchased from Sigma-Aldrich.

(E)-4-Methoxycinnamaldehyde (CAS RN: 24680-50-0), iodine (CAS RN: 7553-56-2) and boron tribromide (CAS RN: 10294-33-4) were purchased from TCI (Tokyo, Japan). 4′,6′-Dimethoxy-2′-hydroxy-3-methyl acetophenone (CAS RN: 23121-32-6) was obtained from Carbosynth (Berkshire, UK). EtOH, DCM, DMSO, EtOAc and CHCl₃ were purchased from KANTO KAGAKU (Tokyo, Japan). DHT was purchased from TCI, and Adione, 11KDHT and 11KAdione were from Steraloids (Newport, RI, USA). Abi and carbenoxolone were obtained from ChemScene (Monmouth Junction, NJ, USA) and Sigma-Aldrich (Saint Louis, MO, USA), respectively. All other chemicals were of the highest grade that could be obtained commercially.