Pr clone pgr 1294

Manufactured by Agilent Technologies

Sourced in Israel

The PR clone PgR 1294 is a laboratory equipment product manufactured by Agilent Technologies. It serves as a device for performing specific functions in a laboratory setting. The core function of this product is to provide the necessary capabilities for laboratory tasks, though the exact details of its intended use are not included in this factual description.

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Lab products found in correlation

Clone do 7, by Agilent Technologies (1 mentions) Ventana anti her2 neu 4b5, by Roche (1 mentions) Er clone 1d5, by Agilent Technologies (1 mentions) Envision system, by Agilent Technologies (1 mentions)

Close spelling variants of this product

PgR 1294 (3 citations)

2 protocols using pr clone pgr 1294

Immunohistochemistry for ER, PR, HER2

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We obtained the ER, PR, and HER2 expression status from the medical records. Monoclonal antibodies ER clone 6F11 (Leica Biosystems, Buffalo Grove, IL), PR clone PgR 1294 (Dako, Carpinteria, CA), and HER2 clone e2-4001 (Thermo Fisher Scientific, Waltham, MA) were used to detect the alpha forms of ER, PR, and HER2, respectively.

Chen H., Singh R.R., Lu X., Huo L., Yao H., Aldape K., Abraham R., Virani S., Mehrotra M., Mishra B.M., Bousamra A., Albarracin C., Wu Y., Roy-Chowdhuri S., Shamanna R.K., Routbort M.J., Medeiros L.J., Patel K.P., Broaddus R., Sahin A, & Luthra R. (2017). Genome-wide copy number aberrations and HER2 and FGFR1 alterations in primary breast cancer by molecular inversion probe microarray. Oncotarget, 8(7), 10845-10857.

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Comprehensive IHC Assay for FFPE Specimens

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An immunohistochemistry (IHC) assay of formalin-fixed and paraffin-embedded (FFPE) specimens was performed using Dako’s EnVision System (Glostrup, Denmark). This is a 2-step method in which the application of the primary antibody is followed by a polymeric conjugate consisting of many secondary antibodies bound directly to a dextran backbone, including ER (clone1D5, DAKO), PR (Clone pgR 1294, DAKO), P53 (Clone DO-7, DAKO) and HER2 (VENTANA anti-HER2/neu(4B5), Roche Diagnostics GmbH). Procedures were provided by the manufacturers and completed on a Roche automated IHC instrument (USA). The antibodies and IHC procedures used in this study were part of a standard IHC panel for a pathology laboratory.

Lian J., Xu E.W., Xi Y.F., Wang H.W., Bu P., Wang J.F, & Wang L.X. (2020). Clinical-Pathologic Analysis of Breast Cancer With PIK3CA Mutations in Chinese Women. Technology in Cancer Research & Treatment, 19, 1533033820950832.

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