Balb c wt mice

Manufactured by Janvier Labs

Sourced in France

BALB/c WT mice are an inbred strain of laboratory mice. They are widely used in biomedical research as a model organism.

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C57bl 6j, by Janvier Labs (1 mentions)

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BALB/c mice (175 citations) BALB/c (30 citations) WT mice (3 citations)

2 protocols using balb c wt mice

VEGF-C Overexpression in Mice

Cited 1 time

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C57BL/6J and BALB/c WT mice were obtained from Janvier. CCSP-rtTA × tet-O–VEGF-C mice (22 (link), 23 ) were backcrossed into the C57BL/6 and BALB/c backgrounds. Prox1-GFP mice were provided by Y.-K. Hong, University of Southern California (29 (link)). All mice were housed under specific pathogen–free conditions. The overexpression of VEGF-C in CCSP-rtTA × tet-O–VEGF-C mice was induced by administration of doxycycline (1 mg/ml, C57BL/6 mice; 2 mg/ml, BALB/c mice) in drinking water (containing 5% sucrose) for 2 weeks, starting at 8 weeks of age.

Ma Q., Dieterich L.C., Ikenberg K., Bachmann S.B., Mangana J., Proulx S.T., Amann V.C., Levesque M.P., Dummer R., Baluk P., McDonald D.M, & Detmar M. (2018). Unexpected contribution of lymphatic vessels to promotion of distant metastatic tumor spread. Science Advances, 4(8), eaat4758.

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Balb/c Mice Husbandry and Ethics

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All mice used in this study have Balb/c genetic background. The Balb/c WT mice were obtained from Janvier Labs (Saint-Berthevin, France). All mice were maintained under specific pathogen-free conditions and had free access to food and water. All experiments were performed in accordance with the German and European laws for animal protection and were approved by the government of Unterfranken, Bavaria (Az. 54-2532.1-2/10).

Krammer S., Yang Z., Zimmermann T., Xepapadaki P., Geppert C.I., Papadopoulos N.G, & Finotto S. (2022). An Immunoregulatory Role of Interleukin-3 in Allergic Asthma. Frontiers in Immunology, 13, 821658.

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