Recombinant human ifn α2b

Manufactured by ProSpec

Recombinant human IFN-α2b is a laboratory-produced protein that is structurally and functionally similar to the naturally occurring human interferon alpha-2b. It is used as a research tool in various biological and medical studies.

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Lab products found in correlation

System microscope bx63, by Olympus (1 mentions)

2 protocols using recombinant human ifn α2b

Interferon-alpha induces gene expression

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Cells were treated with 1000 IU/ml of recombinant human IFN-α2b (Prospec) at different time, and then total RNAs were isolated and used to measure specific mRNA abundance by RT-qPCR.

Liu J., Liu L., Zeng S., Meng X., Lei N., Yang H., Li R., Mu X, & Guo X. (2024). Inhibition of EV71 replication by an interferon-stimulated gene product L3HYPDH. Virus Research, 342, 199336.

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IFN-α2b Inhibits EV-A71 Replication

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Different kinds of cells were treated with 1000 IU/ml of recombinant human IFN-α2b (Prospec) for the indicated time, and then total RNAs were isolated and used to measure specific mRNA abundance by RT-qPCR. To examine the inhibitory effect of IFN on EV-A71, Vero, 293A-SCARB2 and RD cells were infected with EV-A71-GFP and treated with IFN-α2b at 0, 1000 and 10000 IU/ml for 8 h. The replication of the virus EV-A71-GFP was estimated by observing the GFP signal under a fluorescence microscope (System Microscope BX63, Olympus).

Guo X., Zeng S., Ji X., Meng X., Lei N., Yang H, & Mu X. (2022). Type I Interferon-Induced TMEM106A Blocks Attachment of EV-A71 Virus by Interacting With the Membrane Protein SCARB2. Frontiers in Immunology, 13, 817835.

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