S1093

Manufactured by Selleck Chemicals

Sourced in United States

S1093 is a laboratory equipment product offered by Selleck Chemicals. It is designed for use in various scientific and research applications. The core function of S1093 is to facilitate the measurement and analysis of specified parameters within a controlled environment.

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Lab products found in correlation

Igf 2, by Thermo Fisher Scientific (1 mentions) Linsitinib, by Selleck Chemicals (1 mentions) Gsk1904529a, by Selleck Chemicals (1 mentions) Picropodophyllin, by Selleck Chemicals (1 mentions) Entrectinib, by Selleck Chemicals (1 mentions) Rapamycin, by Selleck Chemicals (1 mentions) Gsk126, by Selleck Chemicals (1 mentions)

2 protocols using s1093

Functional Regulation of miRNA Targets

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Hsa-miR-483-5p mimic, YM00473215-ADA, mimic control, YM00479902-ADA, inhibitors hsa-miR-675-5p, 427419-00, hsa-miR-675-3p, 427420-00, hsa-miR-483-5p, 427155-00, hsa-miR-483-3p, 427154-00, hsa-miR-204-5p, 426934-00, hsa-miR-135-5p, 426790-00, hsa-miR-10a-5p, 426651-00, hsa-miR-9-5p, 427460-00, hsa-miR-9-3p, 427461-00, Control B, 199021-00 are from Qiagen, Germantown, MD, USA. Ceritinib, S7083, linsitinib, S1091, entrectinib, S7998, GSK1904529A, S1093, picropodophyllin, S7668 were obtained from Selleck Chemicals, Houston, TX, USA; GSK1838705A, SML0995, was purchased from Millipore-Sigma, Burlington, MA, USA. The primers used for miRNA and mRNA quantification were miR-99b-5p, 4,427,975, miR-483-5p, 4,427,975, miR-675-5p, 4,427,975, IGF-2, 4,331,182, GAPDH, 4,331,182, ThermoFisher Scientific, Waltham, MA, USA.

Uhlmann E.J., Mackel C.E., Deforzh E., Rabinovsky R., Brastianos P.K., Varma H., Vega R.A, & Krichevsky A.M. (2023). Inhibition of the epigenetically activated miR-483-5p/IGF-2 pathway results in rapid loss of meningioma tumor cell viability. Journal of Neuro-Oncology, 162(1), 109-118.

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Pharmacological Interventions in Hypoxia-Ischemia

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Rats in the HI + R and HI + S + R groups received a left-side intra-cerebroventricular injection of the mTOR inhibitor rapamycin (5 µL, 1 mM; S1093, Selleck). Rats in the HI + G and HI + S + G groups received a left-side intra-cerebroventricular injection of the Ezh2 inhibitor GSK126 (5 µL, 50 µM; S7061, Selleck). Rats in the remaining groups were injected with the same volume of vehicle (1% DMSO). The drugs or vehicle were administered 30 mins before HI.

Xue H., Xu Y., Wang S., Wu Z.Y., Li X.Y., Zhang Y.H., Niu J.Y., Gao Q.S, & Zhao P. (2019). Sevoflurane post-conditioning alleviates neonatal rat hypoxic-ischemic cerebral injury via Ezh2-regulated autophagy. Drug Design, Development and Therapy, 13, 1691-1706.

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