C57BL/6JRj, BALB/c and BALB/c nude mice were purchased from Janvier Labs (France). CD4-dnTGFBR2 (stock number 005551) and C57BL/6J (control for CD4-dnTGFBR2) were purchased from The Jackson Laboratory (USA). All mice were kept in specific-pathogen-free conditions. C57BL/6JRj, BALB/c and BALB/c nude mice were females between 9 and 11 weeks old at the start of the experiment. CD4-dnTGFBR2 and C57BL/6J were 9 weeks old at the start of the experiment.
Busenhart P., Montalban-Arques A., Katkeviciute E., Morsy Y., Van Passen C., Hering L., Atrott K., Lang S., Garzon J.F., Naschberger E., Hartmann A., Rogler G., Stürzl M., Spalinger M.R, & Scharl M. (2022). Inhibition of integrin αvβ6 sparks T-cell antitumor response and enhances immune checkpoint blockade therapy in colorectal cancer. Journal for Immunotherapy of Cancer, 10(2), e003465.
+ Open protocol