GCM (purity > 98%) was isolated from the rhizomes of glycyrrhiza using a previously reported method [16 (link)]. ABT-737 was provided by Abbott Laboratories (Abbott Park, IL, USA). Orlistat was purchased from Med Chem Express (Danvers, MA, USA). The primary antibodies of TOPK, p-TOPK, p-AMPK (AMP-activated protein kinase), p-ACC (Acetyl-CoA carboxylase), survivin, p-survivin, Mcl-1 and p-H3 were purchased from Cell Signaling Technology (Danvers, MA, USA). Primary antibody specific for β-actin was purchased from Action Biotech (Beijing, China). The second-antibody specific for Rabbit and Mouse were purchased from MBL International Corporation (Boston, MA, USA). PBK/TOPK-siRNA and control-siRNA were purchased from life technology (Waltham, MA, USA). Survivin-siRNA was purchased from Santa Cruz Biotechnology (Santa Cruz, CA, USA). YM155 was purchased from Med Chem Express.
Ym155
Manufactured by MedChemExpress
Sourced in United States
YM155 is a small molecule that functions as a selective inhibitor of survivin, a protein involved in regulating cell division and apoptosis. This compound is commonly used in research settings to study the role of survivin in various cellular processes and disease models.
Automatically generated - may contain errors
Lab products found in correlation
P ampk, by Cell Signaling Technology (1 mentions)
Mcl 1, by Cell Signaling Technology (1 mentions)
Control sirna, by Thermo Fisher Scientific (1 mentions)
P survivin, by Cell Signaling Technology (1 mentions)
Survivin sirna, by Santa Cruz Biotechnology (1 mentions)
Orlistat, by MedChemExpress (1 mentions)
Abt 737, by Abbott (1 mentions)
Cpd22, by Merck Group (1 mentions)
Penicillin streptomycin, by Corning (1 mentions)
Dulbecco s modified eagle s medium dmem high glucose, by Corning (1 mentions)
Losartan potassium, by Bio-Techne (1 mentions)
Cilengitide, by Bio-Techne (1 mentions)
Ly294002, by Bio-Techne (1 mentions)
Cholesterol, by Merck Group (1 mentions)
β actin, by Cell Signaling Technology (1 mentions)
Sunitinib, by MedChemExpress (1 mentions)
Parp1, by Cell Signaling Technology (1 mentions)
Phospho p70s6k, by Cell Signaling Technology (1 mentions)
Everolimus, by LC Laboratories (1 mentions)
Dspe peg 2000 ome, by Avanti Polar Lipids (1 mentions)
3 protocols using ym155
1
Glycyrrhiza Rhizome-derived GCM Protocol
2
Rat Neonatal H9c2 Cardiac Myoblast Cell Line Protocol
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
The rat neonatal H9c2 cardiac myoblast cell line was obtained from the Korea Cell Line Bank (Seoul, Korea). The cells were cultured in Dulbecco’s modified Eagles medium (DMEM)/high glucose with 10% fetal bovine serum and 1% penicillin-streptomycin (Corning/Mediatech, Inc., Manassas, VA, USA,).
DOX was purchased from Tocris Bioscience (Cat#2252, Bristol, UK). LY294002 (Cat#1130), the PI3K inhibitors, cilengitide (Cat#5870), and losartan potassium (Cat#3798), the integrin inhibitors αvβ3 and αvβ5, and the angiotensin II type 1 receptor (AT1R) inhibitors respectively, were purchased from Tocris Bioscience. The ILK inhibitor Cpd22 (Cat#407331) was obtained from EMD Millipore Corp. (Darmstadt, Germany). The survivin inhibitor YM-155 was purchased from MedChem Express (Cat#HY-10194, Monmouth Junction, NJ, USA).
DOX was purchased from Tocris Bioscience (Cat#2252, Bristol, UK). LY294002 (Cat#1130), the PI3K inhibitors, cilengitide (Cat#5870), and losartan potassium (Cat#3798), the integrin inhibitors αvβ3 and αvβ5, and the angiotensin II type 1 receptor (AT1R) inhibitors respectively, were purchased from Tocris Bioscience. The ILK inhibitor Cpd22 (Cat#407331) was obtained from EMD Millipore Corp. (Darmstadt, Germany). The survivin inhibitor YM-155 was purchased from MedChem Express (Cat#HY-10194, Monmouth Junction, NJ, USA).
3
Liposome Formulation for Cancer Therapy
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
DOPC and DSPE-PEG(2000)-OMe were purchased from Avanti Polar Lipids and Nanosoft Polymers, respectively. Cholesterol was purchased from Sigma. TTP-conjugated lipopeptide was synthesized as described previously [40] . Everolimus and cabozantinib were obtained from LC laboratories. YM155 and sunitinib were obtained from MedChemExpress and Selleckchem, respectively. Antibodies against mTOR, phospho-mTOR, p70S6K, phospho-p70S6K, survivin, ATM, PARP1, CD4, and β-actin were obtained from Cell Signaling Technology. ATR, Chk1, and Chk2 antibodies were obtained from Santa Cruz Biotechnology. CD3, CD8, and Ki67 antibodies were from Abcam, while CD45 antibody was from Biolegend. The phospho-p70S6K antibody used for immunohistochemistry was from Invitrogen. Purified anti-PD-1 antibody [42] was a kind gift from Dr. Keith L. Knutson (Mayo Clinic) who obtained it from the Antibody Core Facility at Mayo Clinic (Rochester, MN).
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!