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Axiom world array 3 platform

Manufactured by Thermo Fisher Scientific

The Axiom World Array 3 platform is a high-throughput genotyping solution designed for large-scale genomic studies. The platform offers comprehensive and customizable coverage for a wide range of applications, including population genetics, genome-wide association studies, and pharmacogenomics research.

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2 protocols using axiom world array 3 platform

1

Genotyping CARDIA and BioVU Cohorts

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CARDIA AA participants were genotyped as part of the Candidate Gene Association Resource (CARe) study using the Affymetrix 6.0 array (Affymetrix, Santa Clara, CA). BioVU AA participants were genotyped using the Affymetrix Axiom Biobank array (Affymetrix, Inc., Santa Clara, CA) and on the Axiom World Array 3 platform (Affymetrix, Inc., Santa Clara, CA). DNA was purified and quantitated by PicoGreen (Invitrogen, Inc., Grand Island, NY).
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2

Genotyping of BioVU and CARDIA Cohorts

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Individuals from BioVU were genotyped on the on the Affymetrix Axiom Biobank array (Affymetrix, Inc., Santa Clara, CA), and BioVU AAs were further genotyped on the Axiom World Array 3 platform (Affymetrix, Inc., Santa Clara, CA) (Supplemental Table 1). Purification and quantification of DNA for BioVU was performed by PicoGreen (Invitrogen, Inc., Grand Island, NY). Individuals from CARDIA were genotyped at the Broad Institute of MIT and Harvard (Cambridge, MA) on the Affymetrix 6.0 array (Affymetrix, Santa Clara, CA).
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