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12 channel birdcage head coil

Manufactured by Siemens
Sourced in Germany

The 12-channel birdcage head coil is a laboratory equipment designed for magnetic resonance imaging (MRI) applications. It is a specialized radio frequency (RF) coil that provides a uniform magnetic field over a predefined volume, enabling high-quality imaging of the human head.

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12 protocols using 12 channel birdcage head coil

1

fMRI Acquisition and Stimulus Presentation

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Functional MRI data were acquired on a research-dedicated 3 Tesla Siemens Trio Tim scanner using a 12-channel birdcage head coil. Participants lay on their backs holding a Cedrus fiber optic button box in their right hand, with their legs supported by a wedge pillow and a blanket provided for warmth if requested. Foam cushions were used to stabilize the position of the head inside the headcoil and to minimize motion. Stimulus presentation and response collection were coordinated using E-Prime software (version 2.0).
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2

Multimodal Brain Imaging at 3T

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All data were collected on the same 3T Siemens MRI scanner at CMU. Six functional (two per sensory modality) and one anatomical scan were acquired per participant. The scanner was equipped with a Siemens 12 channel birdcage head coil, which was used for RF transmit and receive. Functional images were acquired with a T2*-sensitive echo planar imaging pulse sequence (repetition time=1,500 ms, echo time=30 ms, flip angle=75°, 24 slices, 3×3×3 mm voxels, field of view= 192 mm). Anatomical volumes were acquired with a T1-weighted 3D–MPRAGE pulse sequence (1×1×1 mm).
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3

3T Siemens MRI Neuroimaging Protocol

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The same 3T Siemens MRI scanner at the Carnegie Mellon University SIBR was used for both the present and previous study. Six functional (two per sensory modality) and one anatomical scan were acquired per participant. The scanner was equipped with a Siemens 12 channel birdcage head coil, which was used for RF transmit and receive. Functional images were acquired with a T2*-sensitive echo planar imaging pulse sequence (repetition time of 1,500 ms, echo time = 30 ms, flip angle = 75°, 24 slices, 3 × 3 × 3 mm voxels, field of view = 192 mm). Anatomical volumes were acquired with a T1-weighted 3D–MPRAGE pulse sequence (1 × 1 × 1 mm).
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4

Resting-state fMRI Acquisition Protocol

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A MAGNETOM Trio Tim 3.0 T scanner (Siemens Medical Solutions, Germany) with a 12-channel birdcage head coil located at the Shanxi Provincial People’s Hospital was used to acquire rs-fMRI. rs-fMRI was performed using an echo planar imaging (EPI) sequence with the following parameters: TR = 2000 ms, TE = 30 ms, flip angle = 70°, FOV = 24 × 24 cm, matrix = 64 × 64, slice gap = 2 mm, slice thickness = 2 mm, 6 min acquisition. During the resting functional scan, participants were instructed to keep their eyes closed and let their minds wander and not to fall asleep; all participants reported that they did not fall asleep.
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5

Structural MRI Acquisition in PPA and Controls

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Structural MRI scans were acquired from all PPA and healthy control participants on a 3T Siemens TIM Trio scanner using a 12-channel birdcage head coil at the Northwestern University Center for Translational Imaging. A T1-weighted 3D MPRAGE sequence included the following: repetition time = 2300 ms, echo time = 2.91 ms, inversion time = 900 ms, field of view = 256 mm, flip angle = 9° and 1 mm3 voxel resolution collected over 176 sagittal slices. The mean interval of time between the last scan and death (SDI) was 1.96 ± 0.8 years; range 0.61–2.54 years (Table 1).
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6

Functional and Structural Brain Imaging

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All images were collected on a Siemens Trio 3 Tesla full body magnet, using a 12-channel birdcage head coil. Functional blood oxygenation level–dependent (BOLD) images were acquired parallel to the anterior commissure–posterior commissure (AC-PC) line with a T2-weighted echo-planar imaging sequence of 35 interleaved axial slices collected in ascending order (repetition time [TR] = 2000 ms; echo time [TE] = 25 ms; BOLD volumes = 298 for each of the 3 blocks (298x3 = 894); flip angle = 80°; field of view [FOV] = 220 × 220mm; voxel size = 3.4 × 3.4 × 4.0 mm). Structural images were acquired with a T1-weighted three-dimensional (3D) magnetization prepared rapid gradient-echo imaging (MPRAGE) protocol of 192 contiguous sagittal slices collected in an ascending manner parallel to the AC-PC line (TR = 1900 ms; TE = 2.32 ms; flip angle = 9°; FOV = 230 × 230 mm; voxel size = 0.9 × 0.9 × 0.9 mm).
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7

Multimodal Neuroimaging Protocol: 3T MRI and DTI

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A 3-T whole-body Siemens scanner (TrioTim Syngo) with a 12-channel, birdcage head coil was used for anatomical imaging and DTI. Anatomical images were acquired using a T1-weighted, three-dimensional (3D), magnetization-prepared, rapid gradient echo (3D MPRAGE) sequence (repetition time/echo time/inversion time/flip angle = 1670 ms/1.89 ms/900 ms/9°; slice thickness = 1.0 mm; in-plane resolution = 1×1 mm; field-of-view = 250 mm; matrix size = 256×256). DTI was performed in the axial plane using the following parameters: b = 0 and 900 s/mm,2 (link) number of diffusion gradient directions = 30, repetition time = 12,000 ms, echo time = 82 ms, slice thickness = 2 mm, flip angle = 90°, and matrix size = 128×128.
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8

Cortical Thickness Analysis of PPA Patients

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For structural imaging, T1-weighted 3D MP-RAGE sequences (TR=2300 ms, TE=2.91ms, TI=900 ms, flip angle=9°, FoV=256 mm) were used to acquire 176 slices at a slice thickness of 1.0 mm on a 3T Siemens TIM Trio using a 12-channel birdcage head coil. Reconstruction was done with the FreeSurfer image analysis suite, version 5.1 (Fischl & Dale, 2000 ; Fischl, Sereno, Tootell, & Dale, 1999 (link)). Geometric inaccuracies and topological defects were corrected using manual and automatic methods based on validated guidelines (Segonne, Pacheco, & Fischl, 2007 ). Cortical thickness maps of the PPA patients were statistically contrasted against 35 previously described right-handed cognitively healthy volunteers with a similar range of age- and education to identify peak patterns of atrophy (Rogalski et al., 2014 (link)). Differences in cortical thickness between groups were calculated by conducting a general linear model on every vertex along the cortical surface. False Discovery Rate (FDR) for individual patient maps was applied at 0.05 to adjust for multiple comparisons and to detect areas of peak cortical thinning (i.e., atrophy) (Genovese, Lazar, & Nichols, 2002 (link)).
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9

High-Resolution 3T MRI Brain Imaging

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Structural T1-weighted images (MP-RAGE sequences; repetition time (TR) = 2300 ms, echo time (TE) = 2.86 ms, flip angle = 9°, field of view (FOV) = 256 mm; 160 slices with a slice thickness of 1.0 mm) were acquired using a 3T Siemens Trio system with a 12-channel birdcage head coil. Scanning took place at the Center for Translational Imaging at Northwestern University.
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10

MRI FLAIR Imaging and WMH Evaluation

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Two cases had MRI FLAIR scans available prior to death. MRI scans were acquired on a 3T Siemens TRIO system using a 12-channel birdcage head coil. Imaging was performed at the Northwestern University Center for Translational Imaging (CTI). Visual ratings of WMHs were performed by a behavioral neurologist (CO) using the Cardiovascular Health Study (CHS) visual rating scale, which has been previously validated (Manolio et al., 1994 (link); Liao et al., 1997 (link)); the scale is divided into four categories of absent, mild, moderate, or severe WMH based on the convention set by the NACC Uniform Data Set, version 3.0.
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