Physcion

Manufactured by Yuanye Bio-Technology

Sourced in China

Physcion is a laboratory instrument used for the analysis and quantification of chemical compounds. It functions by separating and detecting different substances within a sample through a process known as chromatography. The core purpose of Physcion is to provide accurate and reliable data regarding the chemical composition of various materials.

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Lab products found in correlation

2 protocols using physcion

Authentication of Herbal Medicines in MZRW

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All the six herbal medicines (HMR: RM130121-08; DH: 130524; BS: RM130128-11; KXR: RM121026-04; HP: RM121026-05; ZS: RM121210-11) contained in MZRW were supported and authenticated by PuraPharm Company, Nanning department (Nanning, China). The reference standards of gallic acid, amygdalin, paeoniflorin, hesperidin, neohesperidin, naringin, magnolol, honokiol, aloe emodin, physcion, chrysophanol were purchased from Shanghai Yuan-Ye Bio-technology company (Shanghai, China). Emodin, rhein, albiflorin were purchased from the National Institute for the Control of Pharmaceutical and Biological Products (Beijing, China). The purity of all these reference standards was ≥98.0% (HPLC). HPLC grade of acetonitrile, methanol and formic acid were purchased from Merck (Darmstadt, Germany). Deionized water was purified by the Millipore water purification system (Millipore, Milford, MA, United States). All other reagents used were of analytical grade. Twelve male Sprague-Dawley rats (220–250 g) were kindly provided by the Experimental Animal Center of Chinese University of Hong Kong (Hong Kong). The rats were bred in an environmentally controlled room (22 ± 2°C, relative humidity 50 ± 20%) with a natural light-dark cycle for 7 days before the experiment carried out. The animal study was carried out in accordance with the Guideline for Animal Experimentation of Hong Kong.

Huang T., Ning Z., Hu D., Zhang M., Zhao L., Lin C., Zhong L.L., Yang Z., Xu H, & Bian Z. (2018). Uncovering the Mechanisms of Chinese Herbal Medicine (MaZiRenWan) for Functional Constipation by Focused Network Pharmacology Approach. Frontiers in Pharmacology, 9, 270.

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Isolation and Characterization of Bioactive Compounds

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Gallic acid (#B20851), trans-SG (#B21757), emodin (#B20240), physcion (#B20242), and EG (#B20241) were bought from Yuanye Biotech (China). Cis-SG (#E-0261) and PG (#E-2497) were purchased from Tauto Biotech (China). Methanol and acetonitrile (HPLC grade) were provided by Merck (Germany). Deionized water was obtained using a Milli-Q water system (Millipore, United States). Phosphate acid was from Shanghai Wujin Chemicals (China). RPM, PMP, and PMC were collected from several provinces in China (Supplementary Table S1). These samples were authenticated by Chief Pharmacist Xiu-Feng Shi from Longhua Hospital. Voucher specimens were deposited in a light-absent and well-ventilated room.

Kong W.S., Zhou G., Xu L.W., Wang K., Feng Y.M., Tao L.Y., Xie R.F., Yang M, & Zhou X. (2022). Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury. Frontiers in Pharmacology, 13, 868327.

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