Eudragit l100 55

Manufactured by BASF

Sourced in Germany

Eudragit® L100 55 is a polymeric material used in the production of pharmaceutical and dietary supplement formulations. It is an anionic copolymer based on methacrylic acid and ethyl acrylate. The core function of Eudragit® L100 55 is to provide enteric coating properties, allowing for targeted release of the active ingredients in the intestinal tract.

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Lab products found in correlation

Loratadine, by Merck Group (1 mentions) Kollicoat mae 100p, by BASF (1 mentions) Eudragit rs po, by Evonik (1 mentions) Eudragit rl po, by Evonik (1 mentions) Lutrol f127, by BASF (1 mentions) Kollidon sr, by BASF (1 mentions) Eudragit l100 55, by Evonik (1 mentions) Eudragit epo, by Evonik (1 mentions) Kollidon va64, by BASF (1 mentions) Kollicoat ir, by BASF (1 mentions)

2 protocols using eudragit l100 55

Formulation of Polymeric Nanoparticles

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Loratadine and polyoxyethylene Sorbitan (Polysorbate 80) were obtained from Sigma, USA. Kollicoat® MAE® 100P [poly (methacrylic acid, ethyl methacrylate) 1:1], and Eudragit® L100 55 [poly (methacrylic acid, methyl methacrylate) 1:1], and Polyethylene glycol (PEG 4000) were purchased from Basf (Germany). The other chemicals were pure for analysis provided by Alphatec, Brazil.

Rodriguez Amado J.R., Prada A.L., Duarte J.L., Keita H., da Silva H.R., Ferreira A.M., Sosa E.H, & Carvalho J.C. (2017). Development, stability and in vitro delivery profile of new loratadine-loaded nanoparticles. Saudi Pharmaceutical Journal : SPJ, 25(8), 1158-1168.

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Polymeric Excipients for Controlled Drug Delivery

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Eudragit ® L100-55 (EL), Eudragit ® EPO (EE, after milling/sieving the supplied pellets), Eudragit ® RSPO (RS), and Eudragit ® RLPO (RL, after milling/sieving) were gifted by Evonik (Darmstadt, Germany) and Kollidon ® VA 64 (VA), Kollicoat ® IR, (IR), Kollidon ® SR (SR), Soluplus ® (SL) gifted by BASF (Ludwigshafen, Germany). Extruded polymers are denoted with subscript (ex). Lutrol ® F 127 (polyoxyethylene with polyoxypropylene copolymer) gift by BASF was used as a plasticizer for Eudragit ® L 100-55 only.

Partheniadis I., Toskas M., Stavras F., Menexes G., & Nikolakakis I. (2020). Impact of Hot-Melt-Extrusion on Solid-State Properties of Pharmaceutical Polymers and Classification Using Hierarchical Cluster Analysis. Processes, 8(10), 1208-1208.

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