Polyvinylpyrrolidone

Manufactured by Merck Group

Sourced in United States, Germany, United Kingdom, China, Italy, Spain, Sao Tome and Principe, France, India, Canada, Switzerland, Macao, Japan, Belgium, Sweden, Poland

Polyvinylpyrrolidone (PVP) is a versatile synthetic polymer commonly used in various laboratory applications. It is a water-soluble, non-toxic, and chemically stable compound. PVP's primary function is as a binder, stabilizer, and dispersing agent, helping to maintain the integrity and homogeneity of laboratory samples and solutions.

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Lab products found in correlation

Silver nitrate, by Merck Group (71 mentions) Sodium hydroxide (naoh), by Merck Group (47 mentions) Ethanol, by Merck Group (43 mentions) Sodium borohydride, by Merck Group (42 mentions) Ethylene glycol, by Merck Group (37 mentions) Hydrochloric acid (hcl), by Merck Group (36 mentions) Methanol, by Merck Group (32 mentions) Bovine serum albumin (bsa), by Merck Group (32 mentions) Polyvinyl alcohol (pva), by Merck Group (31 mentions) L ascorbic acid, by Merck Group (29 mentions) Ascorbic acid, by Merck Group (29 mentions) Sodium chloride (nacl), by Merck Group (25 mentions) Dimethyl sulfoxide (dmso), by Merck Group (21 mentions) Phosphate buffered saline (pbs), by Merck Group (19 mentions) Tetraethyl orthosilicate, by Merck Group (18 mentions) Gold 3 chloride trihydrate, by Merck Group (18 mentions) Hydrogen peroxide, by Merck Group (17 mentions) N n dimethylformamide (dmf), by Merck Group (17 mentions) Triton x 100, by Merck Group (17 mentions) Fetal bovine serum (fbs), by Thermo Fisher Scientific (16 mentions)

Spelling variants of this product

Polyvinylpyrrolidone (PVP) (198 citations) Polyvinylpyrrolidone K30 (26 citations) Polyvinylpyrrolidone (PVP K90, (10 citations) Polyvinylpyrrolidone K90 (9 citations) Polyvinylpyrrolidone-40 (8 citations) Polyvinylpyrrolidone K30 (PVP K30), (5 citations) Polyvinylpyrrolidone (PVP10) (3 citations) Polyvinylpyrrolidone K90 (PVP-K90) (2 citations) Polyvinylpyrrolidone-iodine complex (PVP-I, (2 citations) Polyvinylpyrrolidone powder (2 citations)

655 protocols using polyvinylpyrrolidone

Intravascular Blood Replacing Liquid Preparation

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Example 3

The lactic acid buffer solution was added to the gelatin to dissolve the gelatin therein. The in-vivo intravascular blood replacing liquid (flush solution) was prepared by adjusting the concentration of the gelatin to 4 mg/mL. The viscosity of the flush solution at 25 degrees C. was 1.1 mPa·s.

The lactic acid buffer solution was added to the weighed amount of the glycyrrhizin acid monoammonium to prepare a solution of 0.20 mg/mL. In this manner, the flush solution was obtained. The viscosity of the flush solution at 25 degrees C. was 1.0 mPa·s.

By adding 5 g of the polyvinylpyrrolidone (produced by Sigma-Aldrich Corporation) having a molecular weight of 40,000 to 50 g of the RO water and dissolving the polyvinylpyrrolidone in the RO water, the in-vivo intravascular blood replacing liquid (reference example 3) of the present invention was formed. The viscosity of the in-vivo intravascular blood replacing liquid of the reference example 3 was 7.7 mPa·s.

US10376601B2. In-vivo intravascular blood replacing liquid, in-vivo intravascular blood replacing liquid formulation, and prefilled syringe (2019-08-13). TERUMO KABUSHIKI KAISHA [JP]. Inventors: Koji Nakamura [JP], Isao Mori [JP], Masanori Tokida [JP].

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Formulation and Characterization of Blood Replacement Liquids

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Example 2

The lactic acid buffer solution was added to the gelatin to dissolve the gelatin therein. The in-vivo intravascular blood replacing liquid (flush solution) was prepared by adjusting the concentration of the gelatin to 2 mg/mL. The viscosity of the flush solution at 25 degrees C. was 1.0 mPa·s.

As a comparison example 2, a lactate Ringer solution was used. The viscosity of the flush solution at 25 degrees C. was 1.0 mPa·s.

By adding 20 g of the polyvinylpyrrolidone produced by Sigma-Aldrich Corporation) having the molecular weight of 10,000 to 50 g of the RO water and dissolving the polyvinylpyrrolidone in the RO water, the in-vivo intravascular blood replacing liquid (reference example 2) of the present invention was formed. The viscosity of the in-vivo intravascular blood replacing liquid of the reference example 2 was 12.9 mPa·s.

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Almotriptan Formulation Development

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Almotriptan (Emcure Pharmaceuticals limited, Ahmedabad, India), Proloc 15 (Henkel Corporation, Rocky Hill, Connecticut, USA), Eudragit RL 100 and Eudragit RS 100 (Evonik, Darmstadt, Germany) have been provided as gratis samples. Propylene glycol, polyvinylpyrrolidone, polyethylene glycol 400 (PEG 400), methanol, ethyl cellulose, acetone, isopropyl alcohol, dibutyl phthalate and polyvinyl pyrrolidone were commercially purchased (Sigma Aldrich, St. Louis, MO, USA). All other reagents utilized in the experimental investigation were of analytical grade.

Nair A.B., Al-Dhubiab B.E., Shah J., Jacob S., Saraiya V., Attimarad M., SreeHarsha N., Akrawi S.H, & Shehata T.M. (2019). Mucoadhesive buccal film of almotriptan improved therapeutic delivery in rabbit model. Saudi Pharmaceutical Journal : SPJ, 28(2), 201-209.

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Synthesis and Characterization of Silver-Gold Nanostructures

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Analytical grade silver nitrate (AgNO 3 , 99%, Sigma-Aldrich), polyvinylpyrrolidone (PVP, Sigma-Aldrich, M.W. 55,000 g/mol), polyvinylpyrrolidone (PVP, Sigma-Aldrich, M.W. 10,000 g/mol), Ethylene glycol (EG, 99.8%, Sigma-Aldrich), Tetrachloroauric(III) acid trihydrate (HAuCl 4 .3H 2 O, ≥99.9%, Sigma-Aldrich), were used as received. The scanning electron microscopy (SEM) images were obtained using a JEOL field emission gun microscope JSM 6330F operated at 5 kV. The samples were prepared by drop-casting an aqueous suspension containing the nanostructures over a silicon wafer, followed by drying under ambient conditions. UV-Vis spectra were obtained from aqueous suspensions containing the nanostructures with a Shimadzu UV-1700 spectrophotometer. The Ag and Au atomic percentages were measured by inductively coupled plasma optical emission spectrometry (ICP-OES) using a Spectro Arcos equipment.

Ferbonink G.F., Rodrigues T.S., Dos Santos D.P., Camargo P.H.C., Albuquerque R.Q, & Nome R.A. (2018). Correlating structural dynamics and catalytic activity of AgAu nanoparticles with ultrafast spectroscopy and all-atom molecular dynamics simulations. Faraday discussions, 208(0).

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Synthesis and Characterization of Multicomponent Nanomaterials

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Bismuth nitrate pentahydrate (Bi(NO₃)₃·5H₂O), sodium tungstate dihydrate (Na₂WO₄·2H₂O), copper nitrate trihydrate (Cu(NO₃)₂·3H₂O), polyvinylpyrrolidone (PVP, MW 40 000), nickel nitrate tetrahydrate (Ni(NO₃)₂·4H₂O), HCl, NaOH, auramine-O (AO) and methyl green (MG) were purchased from Merck company (Darmstadt Germany). All reagents were analytical grade and used without any further purification, while deionized (DI) water was used for all experiments.

Mosleh S., Dashtian K., Ghaedi M, & Amiri M. (2019). A Bi2WO6/Ag2S/ZnS Z-scheme heterojunction photocatalyst with enhanced visible-light photoactivity towards the degradation of multiple dye pollutants. RSC Advances, 9(52), 30100-30111.

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Synthesis and Characterization of Carbon Nanotube-Based Membranes

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Multiwalled carbon nanotubes (with a length of about 10 to 20 μm, an outer diameter of 20 to 30 nm, and an inner diameter of 5 to 10 nm) were purchased from CNT Co., Ltd., (Yeonsu-Gu, Incheon, Republic of Korea). 250 mL of pyrrole was purchased from Sigma Aldrich (St. Louis, MO, USA). The polysulfone grains for making the ultrafiltration layer were obtained from BASF, Ludwigshafen, Germany. Other materials used include methylphenylenediamine (MPD), dimethylformamide (DMF), camphor sulfonic acid, polyvinylpyrrolidone (PVP), Sodium dodecyl sulfate powder, triethylamine (TEA), and an inorganic solvent was provided, which is Hexane from Merck, Darmstadt, Germany. In order to perform the clogging test, 250 g of bovine serum albumin (BSA) was purchased from Merck. Hollytex 3329 non-woven fabric was obtained from Merck, Germany, with a thickness of 170 μm. Other materials used for the synthesis of Multiwalled carbon nanotubes, including toluene sulfonic acid and aluminum persulfate, were also obtained from Merck.

Amari A., Ali M.H., Jaber M.M., Spalevic V, & Novicevic R. (2022). Study of Membranes with Nanotubes to Enhance Osmosis Desalination Efficiency by Using Machine Learning towards Sustainable Water Management. Membranes, 13(1), 31.

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Amoxicillin Formulation Development

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Amoxicillin trihydrate was provided from Farabi Pharmaceutical Company (Isfahan, Iran). Sodium bicarbonate, citric acid, tartaric acid, polyvinylpyrrolidone (PVP), mannitol, aspartame and polyethylene glycol (PEG-6000) were provided from Merck Company (Germany).

Aslani A, & Sharifian T. (2014). Formulation, characterization and physicochemical evaluation of amoxicillin effervescent tablets. Advanced Biomedical Research, 3, 209.

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Synthesis of Metallic Nanoparticles and Antibacterial Evaluation

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All the chemicals including cobalt acetate tetrahydrate (Co(CH₃COO)₂·4H₂O), silver acetate (CH₃COOAg), ethylene glycol (C₂H₆O₂), polyvinylpyrrolidone (PVP) and ethanol were of research grade and purchased from Merck (Germany). Hydrazinium hydroxide 80% PA (N₂H₄·H₂O) was from Panreac, Barcelona, Spain. The deionized (DI) water was used for synthesis, solution making and other purposes throughout the experiment. Both bacterial strains (Escherichia coli and Bacillus subtilis) were provided by the Microbiological Department of our university.

Kanwal Z., Raza M.A., Riaz S., Manzoor S., Tayyeb A., Sajid I, & Naseem S. (2019). Synthesis and characterization of silver nanoparticle-decorated cobalt nanocomposites (Co@AgNPs) and their density-dependent antibacterial activity. Royal Society Open Science, 6(5), 182135.

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Synthesis and Characterization of PES-TiO2 Nanocomposites

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PES was obtained as a polymer
from Sigma-Aldrich, India. Titanium butoxide (TNBT), poly(vinylpyrrolidone)
(PVP), acetic acid, hydrochloric acid (HCl), and N-methyl-2-pyrrolidone (NMP) were purchased from Merck, India. Lysine,
(3-glycidyloxypropyl) trimethoxysilane GPMS, bovine serum albumin
(BSA), thiazole orange (TO), and propidium iodide (PI) were procured
from Sigma-Aldrich, India.

Venkatesh K., Arthanareeswaran G., Suresh Kumar P, & Kweon J. (2021). Fabrication of Zwitterion TiO2 Nanomaterial-Based Nanocomposite Membranes for Improved Antifouling and Antibacterial Properties and Hemocompatibility and Reduced Cytotoxicity. ACS Omega, 6(31), 20279-20291.

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Synthesis of Functionalized Iron Nitrate Hydrate

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Fe(NO₃)₃·9H₂O, chloroacetic acid, NaOH, thiourea, 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC), N-hydroxysuccinimide (NHS), dimethyl sulfoxide (DMSO), methylene blue (MB), and polyvinylpyrrolidone were prepared from the Merck (Germany). Cell culture materials were obtained from Gibco (Scotland).

Ning S., Zheng Y., Qiao K., Li G., Bai Q, & Xu S. (2021). Laser-triggered combination therapy by iron sulfide-doxorubicin@functionalized nanozymes for breast cancer therapy. Journal of Nanobiotechnology, 19, 344.

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