Biograph mct flow 20 4r pet ct scanner

SSR-PET/CT scans were acquired on a Biograph 64 TruePoint w/TrueV and Biograph mCT Flow 20-4R PET/CT scanner (Siemens Healthineers, Erlangen, Germany). PET/CT scans were initiated 67 ± 11 min after administration of 218 ± 33 MBq [68Ga]Ga-DOTA-TATE PET/CT and 62 ± 10 min after administration of 231 ± 20 MBq [68Ga]Ga-DOTATOC. Data on tracer administration was not available in one case. After intravenous injection of 1.5 times the body weight of contrast agent (Ultravist 300, Bayer Vital GmbH, Leverkusen, Germany or Imeron 350 mg/mL, 2.5 ml/s, Bracco Imaging Deutschland GmbH) diagnostic venous-phase CT scans of the neck, thorax, abdomen, and pelvis (100–190 mAs; 120 kV) were acquired. Patients received diagnostic CT scans without contrast enhancement in cases of known severe allergic reactions to iodinated contrast agent, renal impairment/failure, or hyperthyroidism. Image construction was automatically performed using built-in software. 3 mm-slice reconstructions were used for reading. SSR-expression in PET/CT was assessed visually using the Krenning score.

Whole-body PET/CT images were acquired on a Biograph mCT Flow 20-4R PET/CT scanner (Siemens, Healthcare GmbH, Erlangen, Germany) and a GE Discovery 690 PET/CT scanner (General Electric, Munich, Germany) as previously reported [22 (link),23 (link),24 (link)]. Patients fasted at least 4 h prior to administration of approximately 250 MBq 2-deoxy-2-[¹⁸F]fluoro-D-glucose (2-[¹⁸F]FDG), and emission scan acquisition of the immobilized head and neck, thorax, abdomen, and pelvis started approximately 60 min after intravenous tracer administration. Unless contraindicated, iodine-containing contrast medium (Ultravist 300, Bayer Vital GmbH, Leverkusen, Germany or Imeron 350, 2.5 mL/s, Bracco Imaging Deutschland GmbH, Konstanz, Germany) was administered for diagnostic computed tomography (CT) imaging (100–190 mAs, 120 kV; portal venous phase).

SSR-PET/CT scans were acquired on a Discovery 64-slice PET/CT scanner (GE Healthcare) (n = 33) or a Biograph 64 TruePoint w/TrueV and Biograph mCT Flow 20-4R PET/CT scanner (Siemens, Healthcare GmbH, Erlangen, Germany) (n = 2350) and were initiated approximately 60 min after intravenous administration of a standard amount of approx. 180 MBq radiolabelled somatostatin analogues (68Ga-DOTATOC and 68Ga-DOTATATE). After intravenous injection of contrast agent 1.5 times the body weight (Ultravist 300, Bayer Vital GmbH, Leverkusen, Germany or Imeron 350 mg/mL, 2.5 ml/s, Bracco Imaging Deutschland GmbH, Konstanz, Germany) diagnostic venous-phase CT scans of the neck, thorax, abdomen, and pelvis (100–190 mAs; 120 kV) were acquired. Patients received diagnostic CT scan without contrast enhancement in case of known allergic reactions to iodinated contrast agent, renal impairment/failure or hyperthyreoidism. Imaging construction was automatically performed using built-in software. 3 mm-slice reconstructions were used for reading.