D1CC×D1BC tg mice bred on a DBA/1J background were housed in a pathogen-free animal care facility at Nagoya City University Medical School in accordance with institutional guidelines (38 (link)). iUIP mice were administered pirfenidone (3.6 mg/mouse/day, n = 8), nintedanib (1.8 mg/mouse/day, n = 10), or the vehicle (sterilized 0.5% of methylcellulose, Fujifilm-Wako, Tokyo, Japan, n = 9) orally daily from 6–14 weeks after BMS treatment.
Pirfenidone
Manufactured by Fujifilm
Sourced in Japan
Pirfenidone is a powdered product used in laboratory settings. It is a compound with known pharmaceutical properties, but its core function is to serve as a tool for research and scientific investigation. No further details or interpretation on its intended use can be provided in an unbiased and factual manner.
Automatically generated - may contain errors
Lab products found in correlation
Methylcellulose, by Fujifilm (1 mentions)
Nintedanib, by Fujifilm (1 mentions)
Indomethacin, by Fujifilm (1 mentions)
Nifedipine, by Fujifilm (1 mentions)
Quinine, by Fujifilm (1 mentions)
Ketoprofen, by Fujifilm (1 mentions)
Tamoxifen, by Fujifilm (1 mentions)
Naproxen, by Fujifilm (1 mentions)
Piroxicam, by Fujifilm (1 mentions)
Acetone, by Fujifilm (1 mentions)
Anthracene, by Fujifilm (1 mentions)
Lomefloxacin, by Tokyo Chemical Industry (1 mentions)
Nitrendipine, by Fujifilm (1 mentions)
Sterilized 0.5 w v methyl cellulose solution, by Fujifilm (1 mentions)
Amiodarone, by Tokyo Chemical Industry (1 mentions)
8 methoxypsoralen 8 mop, by Merck Group (1 mentions)
Dimethyl sulfoxide dmso, by Dojindo Laboratories (1 mentions)
Haloperidol, by MP Biomedicals (1 mentions)
Chlorpromazine, by LKT Laboratories (1 mentions)
Nalidixic acid, by LKT Laboratories (1 mentions)
2 protocols using pirfenidone
1
Pirfenidone and Nintedanib Treatment in iUIP Mice
2
Photochemical and Pharmaceutical Compounds
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8-Methoxypsoralen (8-MOP) was purchased from Sigma-Aldrich (St. Louis, MO, USA). Anthracene, indomethacin, ketoprofen, naproxen, nifedipine, nimodipine, nitrendipine, promethazine, piroxicam, quinine, retinol, tamoxifen, pirfenidone, acetone, and sterilized 0.5 w/v% methyl cellulose (MC) solution were from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). Acridin was from Cayman Chemical Company (Ann Arbor, MI, USA). Amlodipine and benzoyl peroxide were purchased from Enzo Life Sciences (Farmingdale, NY, USA). Bufexamac, chlorpromazine, diclofenac, furosemide, gatifloxacin, and nalidixic acid were obtained from LKT Laboratories, Inc. (St Paul, MN, USA). Haloperidol was purchased from MP Biomedicals LLC (Santa Ana, CA, USA). Ibuprofen was from Polysciences Inc. (Warrington, PA, USA). Amiodarone, lomefloxacin, and sparfloxacin were purchased from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Dimethyl sulfoxide (DMSO) was from Dojindo Laboratories (Kumamoto, Japan).
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