Humanomniexpress 12v1 h beadchip

Manufactured by Illumina

The HumanOmniExpress-12v1_H BeadChip is a high-density genotyping microarray designed for genome-wide association studies (GWAS). It is capable of interrogating over 700,000 genetic markers across the human genome.

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Lab products found in correlation

Genomestudio 2011, by Illumina (3 mentions) Infinium assay, by Illumina (2 mentions)

Spelling variants of this product

HumanOmniExpress BeadChip (148 citations) HumanOmniExpress (97 citations) BeadChips (68 citations) HumanOmniExpress-12v1 (20 citations) HumanOmniExpress-12v1 BeadChip (7 citations)

3 protocols using humanomniexpress 12v1 h beadchip

Illumina Infinium Genotyping Assay Protocol

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Genotyping was performed by the Illumina Infinium assay using the Illumina HumanOmniExpress‐12v1_H BeadChip. The results on 730 525 SNPs were analyzed using the software GenomeStudio 2011.1 from Illumina Inc. The average sample call rate per SNP with sample call rate above zero was >99%, and the overall reproducibility was >99.99%. Arrays were processed according to manufacturers' protocol at the SNP&SEQ Technology Platform at Uppsala University and is available on request.25

Wallander K., Liu W., von Holst S., Thutkawkorapin J., Kontham V., Forsberg A., Lindblom A, & Lagerstedt‐Robinson K. (2019). Genetic analyses supporting colorectal, gastric, and prostate cancer syndromes. Genes, Chromosomes & Cancer, 58(11), 775-782.

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Genome-wide Genotyping of Familial CRC

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Genomic DNA was extracted from peripheral blood using standard procedures. Genotyping of in total 587 individuals, familial CRC cases and their relatives, was performed using the Illumina HumanOmniExpress-12v1_H BeadChip. The results, 730,525 SNPs, were analyzed using the software GenomeStudio 2011.1 from Illumina Inc. Average sample call rate per SNP with sample call rate >0 was >99% and the overall reproducibility >99.99%. Arrays were processed according to manufactures protocol at the SNP&SEQ Technology Platform at Uppsala University and available on request (www.genotyping.se).

Thutkawkorapin J., Mahdessian H., Barber T., Picelli S., von Holst S., Lundin J., Valle L., Kontham V., Liu T., Nilsson D., Jiao X, & Lindblom A. (2018). Two novel colorectal cancer risk loci in the region on chromosome 9q22.32. Oncotarget, 9(13), 11170-11179.

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Genotyping of Familial CRC Cases

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Genomic DNA was extracted from peripheral blood using standard procedures. Genotyping of a total of 587 individuals, familial CRC cases and their relatives, was performed by the Illumina Infinium assay using the Illumina HumanOmniExpress-12v1_H BeadChip. The results on 730,525 SNPs, were analyzed using the software GenomeStudio 2011.1 from Illumina Inc. Average sample call rate per SNP with sample call rate >0 was >99% and the overall reproducibility >99.99%. Arrays were processed according to manufactures’ protocol at the SNP&SEQ Technology Platform at Uppsala University and is available on request (www.genotyping.se).

Liu W., Jiao X., Thutkawkorapin J., Mahdessian H, & Lindblom A. (2017). Cancer risk susceptibility loci in a Swedish population. Oncotarget, 8(66), 110300-110310.

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