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Alisertib mln8237

Manufactured by MedChemExpress
Sourced in Germany, United States

Alisertib/MLN8237 is a small molecule inhibitor of the Aurora A kinase enzyme. It is used as a research tool for studying the role of Aurora A kinase in cellular processes.

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2 protocols using alisertib mln8237

1

Inhibitors of Aurora Kinase Evaluations

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Commercial AURK inhibitors were purchased from Sigma-Aldrich, Taufkirchen, Germany (Aurora-A inhibitor I/TC-S 7010, #SML0882) and MedChemExpress, Köln, Germany (Alisertib/MLN8237, #HY10971; Barasertib-HQPA/AZD1152-HQPA, #HY-10126).
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2

Alisertib Effect on HCC Cell Lines

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All human HCC cell lines were purchased from American Type Culture Collection (ATCC, Washington, DC, USA) and cultured in Dulbecco's Modified Eagle's Medium (DMEM, GIBCO-BRL) medium supplemented with 10% fetal bovine serum (FBS), 100 U/mL penicillin, and 100 μg/mL streptomycin in humidified air at 37°C with 5% CO2. Alisertib (MLN8237) was purchased from MedChemExpress (New Jersey, USA).
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