Vitros 5600

Manufactured by Johnson & Johnson

Sourced in United States

The VITROS 5600 Integrated System is a fully automated clinical chemistry and immunoassay analyzer designed for high-volume testing. It offers advanced technologies for efficient sample processing and accurate test results.

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Lab products found in correlation

Cobas 8000, by Roche (1 mentions) Real time hbv dna assay, by Abbott (1 mentions) Liaison xl murex hiv ab ag kit, by DiaSorin (1 mentions) M2000 realtime system, by Abbott (1 mentions) Cobas 6800 system, by Roche (1 mentions) Vacuette, by Greiner (1 mentions) U 2000, by Hitachi (1 mentions)

Spelling variants of this product

VITROS 5600 Integrated System (2 citations)

5 protocols using vitros 5600

Viral Hepatitis and HIV Serological Markers

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Serological markers of HBV (hepatitis B surface antigen (HBsAg) and HBeAg) and hepatitis C virus (HCV), HIV and HDV (anti-HCV, HIV and HDV) infections were tested using commercial immunoassays. At the LCVH, the assays to determine HBV and HCV markers were performed on a COBAS 8000 instrument (Roche Diagnostics, Rotkreuz, Switzerland), and anti-HIV antibodies were determined with the Liaison XL murex HIV Ab/Ag kit (DiaSorin, Saluggia, Italy). At the LCTMS, all these markers were determined on a VITROS 5600 instrument (Johnson and Johnson, New Brunswick, NJ, USA). In both centers, anti-HDV antibodies were tested using the HDV Ab kit (Dia.Pro Diagnostics Bioprobes, Sesto San Giovanni, Italy).
HBV-DNA levels were quantified using the Cobas 6800 System with the cobas HBV assay (Roche Diagnostics, Mannheim, Germany) at LCVH and using the Abbott m2000 RealTime System with the Abbott RealTime HBV DNA assay (Abbott Laboratories, Des Plaines, IL, USA) at LCTMS.

Dopico E., Vila M., Tabernero D., Gregori J., Rando-Segura A., Pacín-Ruíz B., Guerrero L., Ubillos I., Martínez M.J., Costa J., Quer J., Pérez-Garreta J., González-Sánchez A., Antón A., Pumarola T., Riveiro-Barciela M., Ferrer-Costa R., Buti M., Rodríguez-Frías F, & Cortese M.F. (2024). Genotyping Hepatitis B virus by Next-Generation Sequencing: Detection of Mixed Infections and Analysis of Sequence Conservation. International Journal of Molecular Sciences, 25(10), 5481.

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Measuring Gastric and Pancreatic Amylase

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On POD1, POD3, and POD5, we collected 5 mL gastric and pancreatic drain fluid. Gastric fluid was collected via a gastric tube that was left in the gastrointestinal anastomosis; pancreatic fluid was collected via a pancreatic drainage tube that was placed in the major pancreatic duct and supported with a stent. We measured the amylase level in the fluid within the first 30 minutes after collection using an automated biochemical analyzer (VITROS 5600; Johnson & Johnson, 100 Indiago Creek Drive Rochester, New York 14626) with VITROS Chemistry Products AMYL Slides (Johnson & Johnson). The upper limit of normal serum amylase was set at 100 U/L.
Following drain fluid collection, the sample tubes were relabeled to mask any relevant clinical information, and the amylase measurement and ratio analysis were conducted by personnel who were not aware of the patients’ identities and clinical information.

Jin S., Shi X.J., Sun X.D., Zhang P., Lv G.Y., Du X.H., Wang S.Y, & Wang G.Y. (2015). The Gastric/Pancreatic Amylase Ratio Predicts Postoperative Pancreatic Fistula With High Sensitivity and Specificity. Medicine, 94(3), e339.

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Clinical Indicators in Blood Samples

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Demographic data including age, sex, smoking habits, body temperature, and comorbidity data including hypertension, diabetes, and coronary heart disease were collected. Fasting blood samples were extracted by venipuncture to collect clinical indicators in a core laboratory with a standard protocol. An ADVIA2400L automated biochemistry analyzer (Siemens AG, Munich, Germany) was used to measure peripheral WBC, L, PLT, hs-CRP, and D-D. A VITROS5600 (Johnson & Johnson, American) biochemistry analyzer was used to measure TnI. Clinical indicators were measured in a core laboratory with a standard protocol.

Li J., Wang L., Liu C., Wang Z., Lin Y., Dong X, & Fan R. (2021). Exploration of prognostic factors for critical COVID-19 patients using a nomogram model. Scientific Reports, 11, 8192.

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Diagnostic Biomarkers for Cardiac Assessment

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Fingertip blood glucose (Boshi blood glucose meter, TD4279A) was measured in all enrolled patients within 12 hours after admission. Serum BNP concentration was rapidly measured by Boshi Triage bedside rapid quantitative myocardial infarction and heart failure diagnostic instrument (Biosite Systems Ltd., Solihull, UK). Troponin was detected by double antibody sandwich enzyme-linked immunosorbent assay (ELISA), and the kit was provided by Fujian Maixin biological technology co. LTD. D-dimer was detected by immunoturbidimetry with automatic hemagglutination analyzer (cissm CA7000, Japan). Bilirubin, aminotransferase, and creatinine were determined by an automatic dry chemical analyzer (vitros-5600, Johnson & Johnson, New Brunswick, NJ, USA). The reference values of natriuretic peptides and cardiac troponins assays were: BNP: 0 to 100 pg/ml; cTnT: 0 to 0.014 ng/ml); cTnI: 0 to 0.034ng/ml.

Lu W.T., Du W.T., Lu D.S., You J, & Li H.Y. (2022). Predictive value of serum initial brain natriuretic peptide and troponin on functional prognosis in noncardiogenic patients with anterior and posterior circulation cerebral infarction. Arquivos de Neuro-Psiquiatria, 80(10), 985-993.

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Blood Biomarkers During Exercise Training

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Two nurses collected 2 mL of blood from the vein of the antecubital fossa before, in the middle (a pause of 5-min at 60-min of training, Fig. 1), and at the end of the training. From these, 1 mL was collected in a vacuum tube with K₃ + EDTA anticoagulants (Vacuette^®, Greiner Bio-one, Campinas, BRA), and the remainder in a coagulant gel tube (Vacuette^®, Greiner Bio-one, Campinas, BRA). The blood was then centrifuged for 10-min at 3000 rpm to separate plasma (FFA, lactate, and glucose) and serum (creatinine and uric acid). The measurements were performed on the Vitros^® 5600 (Ortho-Clinical Diagnostics, Johnson & Johnson Company, Rochester, USA), except for the FFA which were measured in a spectrophotometer (Hitachi U2000^®, Tokyo, JAP). Biochemical analyses were performed immediately after collection. FFA were used as a marker of lipid catabolism, uric acid as a marker of protein metabolism, and glucose and lactate as carbohydrate metabolism markers.

Carmo K.E., Pérez D.I., Valido C.N., dos Santos J.L., Miarka B., Mendes-Netto R.S., Leite M.M., Antoniêtto N.R., Aedo-Muñoz E.A, & Brito C.J. (2021). Caffeine improves biochemical and specific performance after judo training: a double-blind crossover study in a real judo training situation. Nutrition & Metabolism, 18, 15.

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