Biograph tripoint 64 layer 52 ring hd pet ct scanner

The dual-time ¹⁸F-FDG PET/CT images data of the patients were collected on a Biograph tripoint 64-layer 52-ring HD PET/CT scanner (Siemens, Germany). Before the whole-body scan, the patients were required to fast for at least 6 hours. When their blood sugar was lower than 11.1 mmol/L, ¹⁸F-FDG at the dose of 3.70∼5.55 MBq/kg was injected, and the early scanning was started 50–60 minutes after the injection. The whole-body PET scan covers 5–6 beds, with an acquisition time per bed of about 2.5 minutes, a spatial resolution of 4.07 × 4.07 mm², and a scan thickness of 3 mm. The parameters of the CT scan were a current of 170 mA, a voltage of 120 kV, a spatial resolution of 0.98 × 0.98 mm², and a scan thickness of 3 mm. The PET and CT image matrix size were 168 × 168 and 512 × 512, respectively. After 120–150 minutes, delayed scanning was started. The delayed PET/CT images only contain the head to tail of the pancreas. Patients were required to breathe shallowly during PET/CT scans to reduce the impact of breathing exercises.

All scans were performed before treatment, patients were injected with ¹⁸F-FDG (radiochemical purity ≥95%, Shanghai Atomic Kexing Pharmaceutical Co., Ltd.,) at a dose of 3.70–5.55 MBq/kg. At least 6 h of fasting was applied to all patients prior to scanning, and the blood glucose level was reported below 11.1 mmol/L. All acquisition was performed on a Biograph tripoint 64-layer 52-ring HD PET/CT scanner (Siemens, Germany), 45–60 min after the injection of ¹⁸F-FDG. PET images were performed on 5–6 bed positions with 2.5 min per bed position from mid-skull to mid-thigh. As for CT scanning parameters, slice thickness was 3 mm, acquisition time was 18.67 to 21.93 s, under 170 mA and 120 kV voltage.