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1 palmitoyl 2 oleoyl sn glycero 3 phosphocholine popc

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Sourced in Israel

1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) is a phospholipid commonly used in laboratory research. It is a synthetic lipid molecule composed of a glycerol backbone, a palmitic acid chain, an oleic acid chain, and a phosphocholine head group. POPC is often utilized in studies involving membrane models, liposome formation, and other lipid-based applications.

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Lab products found in correlation

Cholesterol, by Merck Group (1 mentions) 1 2 dioleoyl sn glycero 3 phosphoethanolamine, by Lipoid (1 mentions)

2 protocols using 1 palmitoyl 2 oleoyl sn glycero 3 phosphocholine popc

1

Lipid Membrane Composition Analysis

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The particle membrane included cholesterol (Sigma-Aldrich, Rehovot, Israel), 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) (Lipoid, Ludwigshafen, Germany) and Rhodamine-labeled phospholipid - 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-(lissamine rhodamine B sulfonyl) (ammonium salt) (Avanti Lipids Polar, Alabaster, Alabama).
Krinsky N., Kaduri M., Zinger A., Shainsky-Roitman J., Goldfeder M., Benhar I., Hershkovitz D, & Schroeder A. (2017). Synthetic Cell-like Particles Synthesize Therapeutic Proteins Inside Tumors. Advanced healthcare materials, 7(9), e1701163.
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2

Lipid-based Nanoparticle Formulation

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NeoPhectin AT containing the cationic cardiolipin 1, 3-Bis-(1,2-bis-tetradecyloxy-propyl-3-dimethylethoxyammoniumbromide)-propane 2-ol was purchased from NeoPharm (Waukegan, IL). 1-Palmitoyl-2-oleoyl-sn-glycero-3 phosphocholine (POPC) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) were purchased from Lipoid GmbH or Avanti Polar Lipids. Cholesteryl hemisuccinate (CHEMS) and cholesteryl-4-[[2-(4-morpholinyl)ethyl]amino]-4-oxobutanoate (MOCHOL) were produced by Merck & Cie (Shaffhuasen, Switzerland).
Rodrigueza W.V., Woolliscroft M.J., Ebrahim A.S., Forgey R., McGovren P.J., Endert G., Wagner A., Holewa D., Aboukameel A., Gill R.D., Bisgaier C.L., Messmann R.A., Whitehead C.E., Izbicka E., Streeper R., Wick M.C., Stiegler G., Stein C.A., Monsma D., Webb C., Sooch M.P., Panzner S., Mohammad R., Goodwin N.C, & Al-Katib A. (2014). Development and antitumor activity of a BCL-2 targeted single-stranded DNA oligonucleotide. Cancer Chemotherapy and Pharmacology, 74(1), 151-166.
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