The procedures used in the study conformed to the tenets of the Declaration of Helsinki and to national (Japanese) and institutional (Keio University School of Medicine) regulations. This retrospective study was approved by the Ethics Committee of Keio University School of Medicine (#2012409). While the Vision Van was in service (April 14 to June 29, 2011), examinations were conducted according to the subjects’ needs. The Vision Van is a 40-foot-long, custom-designed, custom-built bus equipped with a slit lamp (BP 900, Haag-Streit Diagnostics, Koenig, Switzerland), binocular indirect funduscope (Keeler Ophthalmic Instruments Inc., Broomall, PA, USA), tonometer (CT-80 noncontact tonometer, Topcon Corporation, Tokyo, Japan), and autorefractor (ARK-1A, Nidek Co, Ltd, Aichi, Japan), as well as a satellite Internet connection and ample storage space. This made it possible to conduct refraction testing, visual acuity and intraocular pressure (IOP) measurements, slit-lamp biomicroscopy, and un-dilated or dilated indirect funduscopy (Figure 3 ). For this study, the medical records of subjects who visited the Vision Van were examined retrospectively in terms of age, sex, reason for visiting the Vision Van, date of visit, diagnosis, and medication(s) prescribed.
Bp 900
Manufactured by Haag-Streit
Sourced in Switzerland, Japan
The BP 900 is a digital blood pressure monitor designed for professional use. It provides accurate measurements of systolic and diastolic blood pressure as well as pulse rate.
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Lab products found in correlation
5 protocols using bp 900
1
Mobile Eye Clinic Protocol
2
Comprehensive Ocular Assessments for MNM
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All patients underwent a thorough history review and ocular examinations. Treatment history was recorded and classified based on the inclusion and exclusion criteria. Ocular examinations involved assessment of intraocular pressure (IOP) (NT-510, NIDEK CO., LTD., Japan), slit-lamp biomicroscopy (BP900, Haag-Streit International, Swiss), indirect ophthalmoscopy (YZ6H, 66Vision.Tech, China), axial length (AL) (AL-scan, NIDEK CO., LTD, Japan), color fundus photograph (AFC-210, Nidek Co., LTD., Japan), and spectral-domain optical coherence tomography (SD-OCT) (Spectralis OCT, Heidelberg Engineering, Germany). OCT-angiography (Spectralis OCT, Heidelberg Engineering, Germany and SVision Imaging, Henan, China), fluorescence, and indocyanine green angiography (Spectralis OCT, Heidelberg Engineering, Germany) were used to diagnose MNM where necessary.
3
Myopic Ocular Characteristics in Young Adults
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This cross-sectional study was approved by the medical ethics committee of Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. The study adhered to the Declaration of Helsinki guidelines. All of the participants gave written informed consent. The study was registered at http://www.chictr.org.cn (registration number ChiCTR2100043611, accessed on 1 March 2021).
We recruited 138 patients from Tongji Hospital from March 2021 to December 2021. The inclusion criteria were: (1) age between 18 and 30 years old; (2) best-corrected visual acuity more than 0.8; (3) spherical equivalent (SE) less than –6.00 D; (4) normal intraocular pressure; (5) clear refractive medium; (6) no history of previous ocular surgery; (7) no ocular diseases other than high myopia.
All participants underwent detailed ocular examinations, including intraocular pressure assessment (IOP) (NT-510, NIDEK Co., Ltd., Tokyo, Japan), refractive error assessment (AR-310A, NIDEK, Tokyo, Japan), slit-lamp biomicroscopy (BP900, Haag-Streit International, Köniz, Switzerland), indirect ophthalmoscope (YZ6H, 66Vision.Tech, Suzhou. China), and axial length (AL) (AL-scan, NIDEK Co., Ltd., Tokyo, Japan). The spherical equivalent (SE) was calculated as the sphere value plus half the cylindrical power.
We recruited 138 patients from Tongji Hospital from March 2021 to December 2021. The inclusion criteria were: (1) age between 18 and 30 years old; (2) best-corrected visual acuity more than 0.8; (3) spherical equivalent (SE) less than –6.00 D; (4) normal intraocular pressure; (5) clear refractive medium; (6) no history of previous ocular surgery; (7) no ocular diseases other than high myopia.
All participants underwent detailed ocular examinations, including intraocular pressure assessment (IOP) (NT-510, NIDEK Co., Ltd., Tokyo, Japan), refractive error assessment (AR-310A, NIDEK, Tokyo, Japan), slit-lamp biomicroscopy (BP900, Haag-Streit International, Köniz, Switzerland), indirect ophthalmoscope (YZ6H, 66Vision.Tech, Suzhou. China), and axial length (AL) (AL-scan, NIDEK Co., Ltd., Tokyo, Japan). The spherical equivalent (SE) was calculated as the sphere value plus half the cylindrical power.
4
Healthy Rabbit Eye Examination
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Twenty male New Zealand White rabbits (Charles River Laboratories, Wilmington, MA), weighing between 2.52 and 3.36 kilograms and ~3.5–4.0 months of age at study start, were housed under a 12/12 hour light/dark cycle with food and water provided ad libitum. All animals were healthy and free of clinically observable ocular disease.
Before assignment of animals to the study, each eye had a pre-screening examination consisting of indirect ophthalmoscopy and corneal slit-lamp examination (BP 900, Haag-Streit AG, Bern, Switzerland) with photography to ensure that only normal corneas were used for experiments and to serve as a baseline for subsequent examinations.
All experimental protocols complied with the Association for Research in Vision and Ophthalmology Statement for the Use of Animals in Ophthalmic and Visual Research, the USDA Animal Welfare Act and the Public Health Service Policy on Humane Care and Use of Laboratory Animals. All animal activities were approved by an Institutional Animal Care and Use Committee (Absorption Systems California, LLC, San Diego, CA).
Before assignment of animals to the study, each eye had a pre-screening examination consisting of indirect ophthalmoscopy and corneal slit-lamp examination (BP 900, Haag-Streit AG, Bern, Switzerland) with photography to ensure that only normal corneas were used for experiments and to serve as a baseline for subsequent examinations.
All experimental protocols complied with the Association for Research in Vision and Ophthalmology Statement for the Use of Animals in Ophthalmic and Visual Research, the USDA Animal Welfare Act and the Public Health Service Policy on Humane Care and Use of Laboratory Animals. All animal activities were approved by an Institutional Animal Care and Use Committee (Absorption Systems California, LLC, San Diego, CA).
5
Ocular Health Assessment Protocol
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General health assessment and gross ocular observations consisted of body weight measurements and a visual appraisal for swelling, discharge, and/or irritation of the eye. Ophthalmic examinations by slit-lamp biomicroscopy (Haag-Streit BP 900) were performed by a board-certified veterinary ophthalmologist following the McDonald–Shadduck scoring system. IOP measurements were performed using a pneumatonometer (Reichert Model 30 Classic) on unanesthetized animals placed in slings at approximately the same time of day for each reading. Prior to all IOP measurements, a 0.5% proparacaine solution was applied as a topical anesthetic. Endothelial cell counts (3–5 scans per eye at different locations) and pachymetry measurements for corneal thickness were taken in parallel on anesthetized animals using a Konan Specular Microscope Model 7700. Prior to these measurements, 1–2 drops of 0.5% proparacaine topical anesthetic solution was applied to the eye.
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