Diethyl ether oxide

Manufactured by Merck Group

Sourced in Germany

Diethyl ether oxide is a colorless, volatile, and flammable liquid chemical compound. It has a distinctive sweet odor and is commonly used as a solvent in various industrial and laboratory applications. The core function of diethyl ether oxide is to serve as a versatile solvent for organic compounds, facilitating chemical reactions and extraction processes.

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Diethyl ether (590 citations)

5 protocols using diethyl ether oxide

Biochemical Assay Protocol for Venlafaxine and Dexamethasone

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Venlafaxine hydrochloride was a gift from Daroupakhsh Pharmaceutical Co. (Tehran, Iran). Dexamethasone was also a gift from Raha Pharmaceutical Co. (Isfahan, Iran). Reserpine, hexadecyl trimethyl-ammonium bromide (HTAB) and O-dianisidine dihydrochloride were purchased from Sigma Chemical Co. (St. Louis, Mo, USA).
Formalin solution 35% w/w, glacial acetic acid and diethyl ether oxide were supplied by Merck (Darmstadt, Germany). All other solvents and chemicals were of analytical grade.

Minaiyan M., Hajhashemi V., Rabbani M., Fattahian E, & Mahzouni P. (2015). Effect of venlafaxine on experimental colitis in normal and reserpinised depressed rats. Research in Pharmaceutical Sciences, 10(4), 295-306.

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Inflammatory Cytokine Measurement Protocol

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Doxepin hydrochloride (Sigma, USA) and dexamethasone hydrochloride (Darupakhsh Company, Iran) were dissolved in isotonic saline. Formalin, glacial acetic acid and diethyl ether oxide (Merck, Darmstadt, Germany) were also used.
Dibasic potassium phosphate (Merck, Germany), monobasic potassium phosphate (Merck, Germany), hexadecyl trimethyl ammonium bromide (HTAB) and o-dianisidine dihydrochloride (o-dianisidine) (Sigma Chemical Co., St. Louis, Mo, USA), hydrogen peroxide (H₂O₂) was used for determination of myeloperoxidase (MPO) activity.
TNF-α, IL-6 and IL-1β kits (Boster, USA) were used for measurement of the cytokines.
Ketamine and xylazine vials (Alfasan, The Netherlands) were used for inducing anesthesia in rats.

Zabihi M., Hajhashemi V., Talebi A, & Minaiyan M. (2017). Evaluation of central and peripheral effects of doxepin on acetic acid-induced colitis in rat and the involved mechanisms. EXCLI Journal, 16, 414-425.

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Prednisolone and Mesalamine Powders Analysis

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Prednisolone and mesalamine powders were purchased from Iran Hormone Company (Tehran, Iran). o-dianisidine dihydrochloride (ODD) and hexadecyl trimethyl ammonium bromide (HTAB) were purchased from Sigma Company (St. Louis, USA). Ethanol, diethyl ether oxide, glacial acetic acid, and formaldehyde were purchased from Merck Company (Darmstadt, Germany). Normal saline was purchased from Shahid-Ghazi Company (Tabriz, Iran).

Niknami E., Sajjadi S.E., Talebi A, & Minaiyan M. (2020). Protective Effect of Vitis vinifera (Black Grape) Seed Extract and Oil on Acetic Acid-Induced Colitis in Rats. International Journal of Preventive Medicine, 11, 102.

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Mesalazine and Dexamethasone Powder Characterization

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The powders of mesalazine (MES) and dexamethasone (Dex) were procured from Iran-Hormone Pharmaceutical Co. (Tehran, Iran). Orto-dianizidin dihydrocholoride (ODD), hexa-decyl trimethyl ammonium bromide (HTAB), and Folin–Ciocalteu reagent were bought from Sigma Co. (St. Louis, MO, USA). Formaldehyde, glacial acetic acid, ethanol (96%), and diethyl ether oxide were purchased from Merck Co. (Darmstadt, Germany).

Hadavi-Siahboomi M., Yegdaneh A., Talebi A, & Minaiyan M. (2022). Ulcer-Healing Effect of Hydroalcoholic Extract and Essential Oil of Achillea millefolium L. on Murine Model of Colitis. International Journal of Preventive Medicine, 13, 155.

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Mesalamine and Dexamethasone Powder Evaluation

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Mesalamine and dexamethasone powders were received as a gift from Iran Hormone Company (Tehran, Iran). O-dianisidine dihydrochloride (ODD) and hexadecyl trimethyl ammonium bromide (HTAB) were purchased from Sigma Company (St. Louis, USA). Ethyl and methyl alcohols, diethyl ether oxide, n-hexane, glacial acetic acid, and formaldehyde were procured from Merck Company (Darmstadt, Germany). Normal saline made in Shahid-Ghazi Corporation (Tabriz, Iran) was prepared from a local pharmacy.

Jalalipour M., Yegdaneh A., Talebi A, & Minaiyan M. (2022). Salvia officinalis leaf extracts protect against acute colitis in rats. Research in Pharmaceutical Sciences, 17(4), 350-359.

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