Agilent lc msd trap xct plus system

Manufactured by Agilent Technologies

The Agilent LC/MSD Trap XCT Plus system is a liquid chromatography-mass spectrometry (LC/MS) instrument designed for high-performance analysis. It combines liquid chromatography with an ion trap mass spectrometer to provide sensitive and accurate quantitative and qualitative analysis of a wide range of compounds.

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Lab products found in correlation

Unity spectrometers, by Agilent Technologies (4 mentions)

Close spelling variants of this product

LC/MSD Trap XCT Plus). MSD Trap XCT Plus LC/MSD system Agilent LC systems XCT Plus

4 protocols using agilent lc msd trap xct plus system

Characterization of Organic Compounds

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All chemicals were reagent grade. ¹H NMR and ¹³C NMR spectra were obtained on Varian (Palo Alto, CA) Unity spectrometers at 400 and 500 MHz for ¹H and at 100 and 125 MHz for ¹³C. Elemental analyses were carried out in the University of Illinois Microanalysis Laboratory. HPLC/MS analyses were performed by using an Agilent LC/MSD Trap XCT Plus system (Agilent Technologies, Santa Clara, CA) with an 1100 series HPLC system including a degasser, an autosampler, a binary pump, and a multiple wavelength detector. All final compounds were ≥95% pure as determined by quantitative spin count NMR (qNMR) or HPLC-MS and structures were characterized by ¹H NMR and HRMS.

Desai J., Wang Y D.r., Wang K D.r., Malwal SR D.r, & Oldfield E. (2016). Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth. ChemMedChem, 11(19), 2205-2215.

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Synthesis and Characterization of Novel Compounds

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All chemicals were reagent grade. ¹H NMR and ¹³C NMR spectra were obtained on Varian (Palo Alto, CA) Unity spectrometers at 400 and 500 MHz for ¹H and at 100 and 125 MHz for ¹³C. Elemental analyses were carried out in the University of Illinois Microanalysis Laboratory. HPLC/MS analyses were performed by using an Agilent LC/MSD Trap XCT Plus system (Agilent Technologies, Santa Clara, CA) with an 1100 series HPLC system including a degasser, an autosampler, a binary pump, and a multiple wavelength detector. All final compounds were ≥90% pure as determined by quantitative spin count NMR (qNMR) and structures were characterized by ¹H NMR and HRMS. The synthesis and characterization of all new compounds (3-50) are shown in the Supporting Information.

Li K., Wang Y., Yang G., Byun S., Rao G., Shoen C., Yang H., Gulati A., Crick D.C., Cynamon M., Huang G., Docampo R., No J.H, & Oldfield E. (2015). Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors. ACS infectious diseases, 1(5), 215-221.

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Characterization of Pentamidine and Netropsin

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All chemicals were reagent grade. Pentamidine and netropsin were purchased from Aldrich. ¹H NMR and ¹³C NMR spectra were obtained on Varian (Palo Alto, CA) Unity spectrometers at 400 and 500 MHz for ¹H and at 100 and 125 MHz for ¹³C. Elemental analyses were carried out in the University of Illinois Microanalysis Laboratory. HPLC/MS analyses were performed by using an Agilent LC/MSD Trap XCT Plus system (Agilent Technologies, Santa Clara, CA) with an 1100 series HPLC system including a degasser, an autosampler, a binary pump, and a multiple wavelength detector. All final compounds were ≥95% pure as determined by elemental analysis or analytical HPLC/MS analysis and were also characterized by ¹H NMR and HRMS.

Zhu W., Wang Y., Li K., Gao J., Huang C.H., Chen C.C., Ko T.P., Zhang Y., Guo R.T, & Oldfield E. (2015). Antibacterial Drug Leads: DNA and Enzyme Multi-Targeting. Journal of medicinal chemistry, 58(3), 1215-1227.

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Synthesis and Characterization of Benzoic Acids

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All chemicals were reagent grade. ¹H and ¹³C NMR spectra were obtained on Varian (Palo Alto, CA) Unity spectrometers at 400 or 500 MHz for ¹H and at 100 or 125 MHz for ¹³C. Elemental analyses were carried out in the University of Illinois Microanalysis Laboratory. HPLC-MS analyses were performed by using an Agilent LC/MSD Trap XCT Plus system (Agilent Technologies, Santa Clara, CA) with an 1100 series HPLC system including a degasser, an autosampler, a binary pump, and a multiple wavelength detector. All final compounds were ≥95% pure as determined by HPLC and structures were characterized by ¹H NMR, LC-MS and HRMS. More detailed information on the synthesis of benzoic acids can be found in the Supporting Information.

Ricci C.G., Liu Y.L., Zhang Y., Wang Y., Zhu W., Oldfield E, & McCammon J.A. (2016). Dynamic Structure and Inhibition of a Malaria Drug Target: Geranylgeranyl Diphosphate Synthase. Biochemistry, 55(36), 5180-5190.

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