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Angioplex octa device

Manufactured by Zeiss
Sourced in United States

The Angioplex OCTA device is a non-invasive imaging tool designed for ophthalmological applications. It utilizes optical coherence tomography angiography (OCTA) technology to capture high-resolution, three-dimensional images of the retinal and choroidal blood vessels. The device provides detailed visual information about the vascular structures within the eye, enabling healthcare professionals to assess various ocular conditions.

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2 protocols using angioplex octa device

1

Measuring Retinal Layer Thickness Using OCT

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To measure the thickness of the ganglion cell-inner plexiform layer (GCIPL) and the peripapillary retinal nerve fiber layer (pRNFL), the 512×128 scanning protocol was utilized in a Zeiss HD-OCT with an Angioplex OCTA device (Carl Zeiss Meditec, Dublin, CA, USA) (Figure 1). The GCIPL thickness was measured using an elliptical partition and the pRNFL thickness was measured using a quadrantal partition; measurements were obtained from Zeiss OCT reports. GCIPL and RNFL thickness were measured at baseline (pre-operation, PRE), post-operative day (POD) 1, and POD 7.
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2

Normative Ocular and Vascular Data

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This study initially included 588 eyes from 294 healthy, young volunteers who visited the Armed Forces Capital Hospital for a health screening checkup. All subjects underwent comprehensive ophthalmic examinations including a slit-lamp biomicroscopy, refraction,best-corrected visual acuity (BCVA), intraocular pressure (IOP). Additionally, central corneal thickness (NT-530, NIDEK Co., LTD, Gamagori, Aichi, Japan), axial length (IOLMaster, Carl Zeiss Meditec, Dublin, CA, USA) were measured, and OCT and OCTA using the Zeiss Cirrus 5000 (Carl Zeiss Meditec, Dublin, CA, USA) was performed. All subjects underwent a 3 × 3 mm angiography scan in the peripapillary area using the AngioPlex OCTA device from the Zeiss Cirrus 5000 system, without pupil dilation, and no eyedrops or gels were used to degrade the image quality. The excluded subjects were those with a history of systemic disease including diabetes and hypertension, a history of neuro-ophthalmic or retinal disease, media opacity, glaucoma, a history of ocular trauma, an IOP > 21 mmHg, BCVA < 20/25, OCTA scan with an SS < 7, a, and the presence of a segmentation error in the OCTA scan. If both eyes met the inclusion criteria, one eye was randomly selected. Finally, 259 eyes from 259 healthy, young subjects were included in this study.
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