Haucl4

Manufactured by Strem Chemicals

Sourced in United States

HAuCl4 is a chemical compound used in various laboratory applications. It is a yellow crystalline solid that is soluble in water and some organic solvents. HAuCl4 is commonly used as a precursor for the synthesis of gold nanoparticles and other gold-containing materials.

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Lab products found in correlation

Deuterated solvent, by Cambridge Isotopes (3 mentions) Benzyl bromide, by Merck Group (2 mentions) Silver oxide, by Merck Group (2 mentions) Ethyl iodide, by Merck Group (2 mentions) 4 5 diphenylimizadole, by Thermo Fisher Scientific (2 mentions) Lithium bis trimethyl silyl amide, by Thermo Fisher Scientific (2 mentions) Nanodrop one, by Thermo Fisher Scientific (2 mentions) Tcep solution, by Merck Group (1 mentions) Nova nano sem 450 instrument, by Thermo Fisher Scientific (1 mentions) Fetal bovine serum (fbs), by Thermo Fisher Scientific (1 mentions) Chi660c electrochemical workstation, by CH Instruments (1 mentions) Tmb substrate, by Neogen (1 mentions) Ru nh3 6 cl3, by Merck Group (1 mentions) Axis ultrabld instrument, by Shimadzu (1 mentions) K3fe cn 6, by Merck Group (1 mentions)

Close spelling variants of this product

Hydrogentetrachloroaurate(III) hydrate (HAuCl4) Hydrogen tetrachloroaurate(III) (HAuCl4)

6 protocols using haucl4

Electrochemical Biosensing of Biomarkers

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All nucleotide sequences used (Table 1 and Table S1, ordered from Sangon Biotech, Shanghai, China): tris (2-carboxyethyl) phosphine hydrochloride, named TCEP solution (Sigma-Aldrich, Shanghai, China); poly-HRP40 (streptavidin modified), named SA-polyHRP (Fitzgerald Industries International Inc., New Castle, DE, USA); TMB Substrate (Neogen, KY, USA); HAuCl₄ (99.8% Au, Strem Chemicals Inc., Bischheim, France); fetal bovine serum, named FBS (Invitrogen, Carlsbad, CA, USA); all chemical buffer (Sangon Biotech, Shanghai, China). We also used: 16-mutichannel screen-printed carbon electrode, named 16-SPCE (CH Instruments, Inc., Shanghai, China); CHI-660C electrochemical workstation (CH Instruments, Inc., Shanghai, China); NanoDrop One (Thermo Fisher Scientific Inc., Tumwater, WA, USA); Nova nanoSEM 450 instrument (FEI Company, Rockville, MD, USA); and AFM Multimode 8 instrument (Bruker, Billerica, CA, USA).
Human serum samples were derived from healthy human blood, which was donated by volunteers. First, the whole blood was centrifuged at 3500 rpm for 10 min, then the supernatant was collected and kept at 4 °C for later use.

Wang C., Wang W., Xu Y., Zhao X., Li S., Qian Q, & Mi X. (2022). Tetrahedral DNA Framework-Programmed Electrochemical Biosenors with Gold Nanoparticles for Ultrasensitive Cell-Free DNA Detection. Nanomaterials, 12(4), 666.

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Synthesis of Gold and Titanium Complexes

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[AuCl(tht)],^{[52 ]} [AuX(NHC)] (X = Cl, Br),^{[20 (link),21 ]} and Cp₂TiMe₂^{[53 ]} were prepared as previously reported. Chemicals were purchased as indicated: Cp₂TiCl_2, H[AuCl₄] (STREM Chemicals), 4-mercaptobenzoic acid (H₂mba) and Methyl Lithium solution (1.6M) (Sigma Aldrich). Reaction solvents were purchased anhydrous from Fisher Scientific (BDH, ACS Grade) and Sigma-Aldrich, used without further purification, and dried in a SPS machine and kept over molecular sieves (3 Å, beads, 4–8 mesh), otherwise over sodium if necessary. Deuterated solvents were purchased from Cambridge Isotope Laboratories, Inc. and were kept over molecular sieves (3 Å, beads, 4–8 mesh). Celite (Celite 545, Diatomaceous Earth) was purchased from VWR International and used as received.

Curado N., Giménez N., Miachin K., Aliaga-Lavrijsen M., Cornejo M.A., Jarzecki A.A, & Contel M. (2019). Preparation of Titanocene-Gold Compounds Based on Highly Active Gold(I)-N-Heterocyclic Carbene Anticancer Agents. Preliminary in vitro Studies in Renal and Prostate Cancer Cell lines.. ChemMedChem, 14(11), 1086-1095.

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Synthesis and Characterization of Nanocomposites

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GO was purchased from Nanjing XFNANO Materials Tech Co., Ltd. (Nanjing, China), while EDOT, DA, UA, AA, K₃Fe(CN)₆, and Ru(NH₃)₆Cl₃ were purchased from Sigma-Aldrich (St. Louis, MO, USA). HAuCl₄ was purchased from Strem Chemicals, Inc. (Newburyport, MA, USA). All reagents were of analytical grade, and 18.2 MΩ cm Milli-Q water was used throughout the experiments.
The surface morphologies of the nanocomposites were obtained by TEM (JEOL JEM-2100Plus microscope) and SEM (Gemini SEM 500 microscope). The crystal structures were characterized by XRD using a LabX XRD-6100 system (Shimadzu, Kyoto, Japan). The element compositions of the nanocomposites were analyzed by XPS (AXIS ULtrabld instrument; Kratos, Manchester, UK). Electrochemical measurements were obtained using a CHI760 electrochemical workstation with a conventional three-electrode system, where platinum wire served as the auxiliary electrode, a saturated Ag/AgCl electrode was used as the reference electrode, and a bare or modified GCE (diameter=3.0 mm) served as the working electrode. Sodium phosphate buffer saline (PBS; 10 mM, pH=7.4) was used as electrolyte solution.

Pan J., Liu M., Li D., Zheng H, & Zhang D. (2021). Overoxidized poly(3,4-ethylenedioxythiophene)–gold nanoparticles–graphene-modified electrode for the simultaneous detection of dopamine and uric acid in the presence of ascorbic acid. Journal of Pharmaceutical Analysis, 11(6), 699-708.

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Synthesis of Gold Compound Au-1

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The preparation of gold compound Au-1 was was performed following a reported synthetic method. 53 (link) H[AuCl 4 ] was purchased from Strem Chemicals (Newburyport, MA). Benzyl bromide, ethyl iodide, and silver oxide were purchased from Sigma Aldrich (St. Louis, MO). 4,5-diphenylimizadole and lithium bis(trimethyl silyl)amide were purchased from Alfa Aesar (Haverhill, MA). Reaction solvents were purchased anhydrous from Fisher Scientific (BDH, ACS Grade) and Sigma-Aldrich. Solvents were dried in a SPS machine, and kept over molecular sieves (3 Å, beads, 4-8 mesh); otherwise over sodium, if necessary. Deuterated solvents were purchased from Cambridge Isotope Laboratories, Inc., and were kept over molecular sieves (3 Å, beads, 4-8mesh). Celite (Celite 545, Diatomaceous Earth) was purchased from VWR International and used as received.

Marciano Y., Nayeem N., Dave D., Ulijn R.V, & Contel M. (2023). N-Acetylation of Biodegradable Supramolecular Peptide Nanofilaments Selectively Enhances Their Proteolytic Stability for Targeted Delivery of Gold-Based Anticancer Agents. ACS biomaterials science & engineering, 9(6).

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Synthesis of Gold Nanoparticles

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Dimyristoylphosphatidylcholine (DMPC) and 10, 12-tricosadiynoic acid were purchased from NOF (Tokyo, Japan) and Alfa-Aesar (Ward Hill, MA, USA), respectively. HAuCl4 was purchased from Strem Chemicals Inc (Newburyport, MA, USA) and used without further purification. Bovine serum albumin (pooled, mixed gender) was purchased from Biochemed Pharmaceuticals Inc (Winchester, VA, USA) and kept at −20 °C for further use. All other chemicals were of analytical grade and used as received.

Gu C., Geng Y., Zheng F, & Rotello V.M. (2020). Rapid evaluation of gold nanoparticle-lipid membrane interactions by the lipid/polydiacetylene vesicles sensor. The Analyst, 145(8), 3049-3055.

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Synthesis of Gold Compounds

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Gold compounds 1 and 2 were prepared as previously reported.^{69 ,70 (link)} Chemicals were purchased as indicated: H[AuCl₄] (Strem Chemicals, Newburyport, MA), benzyl bromide, ethyl iodide, and silver oxide (Sigma Aldrich, St. Louis, MO), 4,5-diphenylimizadole and lithium bis(trimethyl silyl)amide (Alfa Aesar, Haverhill, MA). Reaction solvents were purchased anhydrous from Fisher Scientific (BDH, ACS Grade) and Sigma-Aldrich, used without further purification, dried in a SPS machine, and kept over molecular sieves (3 Å, beads, 4–8 mesh), otherwise over sodium if necessary. Deuterated solvents were purchased from Cambridge Isotope Laboratories, Inc., and were kept over molecular sieves (3 Å, beads, 4–8mesh). Celite (Celite 545, Diatomaceous Earth) was purchased from VWR International and used as received.

Colas B., Olivieri I, & Riba M. (1997). Centaurea corymbosa, a cliff-dwelling species tottering on the brink of extinction: A demographic and genetic study. Proceedings of the National Academy of Sciences of the United States of America, 94(7), 3471-3476.

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