All MD-CT examinations were performed on an MD-CT unit with 64 rows (Philips Brilliance 64, detector collimation: 64 × 0.625 mm, tube current: 650 mAs/rotation, tube voltage: 120 kV, primary reconstructed slice thickness: 0.9 mm, increment: 0.45 mm, rotation time 0.4 s, pitch: 0.2, retrospective ECG gating). A 90 ml bolus of an iodine-containing contrast agent (Solutrast 370, Bracco Imaging, Germany) was injected intravenously with an injection rate of 6 ml/s followed by a saline bolus with an injection rate of 4 ml/s. After detection of the contrast bolus (bolus track technique with 1 frame/second, threshold value of 150 HU of the ascending aorta, measurement field at the level of the tracheal bifurcation), image acquisition was started with a time delay of 6 seconds. Patients were monitored during the entire examination using ECG and pulse oximeter. Systolic images (30 % of RR interval) and diastolic images (75 % of RR interval) were reconstructed for image analysis.
Solutrast 370
Manufactured by Bracco
Sourced in Germany
Solutrast 370 is a water-soluble iodinated contrast medium used for radiographic procedures. It is a sterile, aqueous solution containing the active ingredient iopromide, which is a non-ionic iodinated contrast agent.
Automatically generated - may contain errors
4 protocols using solutrast 370
1
Cardiac CT Angiography Protocol
2
Extracranial Vascular Imaging by 64-Slice CT
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A 64-slice CT scanner (SOMATOM Sensation 64, Siemens Healthineers, Erlangen, Germany) was used. Multislice CT acquisition was performed using isotropically resolved contrast media-enhanced angiographic imaging of extracranial vessels. To achieve optimal timing of arterial contrast bolus tracking, a region of interest within the aortic arch and a threshold set to 120 Hounsfield units (HU) were used. The procedure utilized 80 cc intravenous contrast of Solutrast® 370 (Bracco Imaging Deutschland GmbH, Konstanz, Germany) or Ultravist® 370 (Schering/Bayer Pharma AG, Berlin, Germany) with an injection rate of 3–4 cc/s followed by 50 cc sodium chloride injection. Other parameters were as follows: 100 KV, effective 160 mAs, rotation time 0.5 s, detector collimation 0.6 mm, reconstructed slice thickness 0.75 mm, pitch 1.2, kernel H20, and image acquisition order caudal cranial.
3
Cardiac CT Imaging of Porcine Heart
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The MuCLS was tuned to 35.0 keV x-ray peak energy, with a flux of approximately 1.1 × 106 photons/s mm2 at the sample position. A spectrum of the x-ray beam acquired with an Amptek X-123 detector is shown in Fig. 1(a) . An excised porcine heart was placed in a waterbath (photograph shown in Fig. 3(a) ) and iodine-based contrast agent (Solutrast 370, Bracco Imaging Deutschland GmbH) was injected into the coronary artery. A flatpanel detector (Varian PaxScan 2520DX, Varian Medical Systems Inc., USA), equipped with a Gd2O2S scintillator, with a pixel size of 127 μm was placed at 16.5 m from the x-ray source point. The sample-detector distance was 80 cm, corresponding to an effective pixel size of 121 μm. An image was acquired with an exposure time of 1 second and flatfield-corrected.
4
Multimodal CT Imaging in Stroke
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All CT examinations were performed on clinical multidetector CT scanners (Brilliance 16 CT, IQon Spectral CT, iCT 256, Philips Healthcare). CT examinations included non-enhanced CT, perfusion CT (optional) and CT angiography after injection of intravenous contrast agent (50 ml; Solutrast 370, Bracco Imaging) followed by 50 ml isotonic saline solution in bolus technique with bolus tracking in a single setting. Separate contrast media boluses in the same technique were used when both CT perfusion and CT angiography were performed. Standard parameters of image acquisition were as follows: slice thickness 1 or 2 mm, tube voltage 120 kVp, tube current (exposure time product) 82 mAs. Additionally, computer-assisted automated ASPECTS (Alberta Stroke Program Early CT Score) measurements were performed for each patient as a supportive tool for the assessment of early ischemic changes.
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