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Phenacetin

Manufactured by J&K Scientific
Sourced in China

Phenacetin is a chemical compound that serves as an analgesic and antipyretic agent. It is a crystalline solid substance that is soluble in organic solvents. Phenacetin is utilized in various scientific and research applications.

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2 protocols using phenacetin

1

Comparative Analysis of Red Wine Compounds

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Five red wines,
Bordeaux (year 2015, France, made with Merlot, Cabernet Sauvignon
and Cabernet Franc, coded as F), Mendoza (year 2016, Argentina, made
with Malbec, coded as AG), Zhangyu (year 2015, China, made with Cabernet
Gernischt, coded as C), Jacob’s creek classic cabernet (year
2015, Australia, made with Shiraz and Cabernet Sauvignon, coded as
A1), and Jacob’s creek classic merlot (year 2015, Australia,
made with Merlot, coded as A2) were purchased from local supermarkets
in Shanghai (China). The wines were stored at room temperature in
the dark until analysis and immediately analyzed after opening the
bottle to ensure minimum oxidation. Each wine was duplicated in bottle
for the measurement, and all of the experiments were performed at
least in triplicate. Phenacetin (Mw 179.22,
99%) was obtained from J&K Scientific (Beijing, CN). Dextromethorphan
(Mw 271.40, 99%) was obtained from Fluorochem
(Derbyshire, U.K.). Caffeine (Mw 194.19,
≥98%) was obtained from Sigma (St. Louis, USA). Deionized water
(18.2 MΩ cm) was purified by a Smart-Q deionized water system
(Hitech pure water technology, Shanghai, China) and used in all aqueous
solutions.
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2

Analytical Method for Xenobiotic Metabolism

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Phenacetin, bupropion, tolbutamide, dextromethorphan, midazolam, chlorzoxazone, and the diazepam (all purity> 98%) that used as internal standards (ISs) were purchased from J&K Scientific Ltd. (Beijing, China). Vonoprazan was purchased from Beijing Sunflower Scientific Ltd. (Beijing, China). Hydroxybupropion and hydroxymidazolam were purchased from Sigma-Aldrich (St Louis, USA). Dextrorphan, hydroxytolbutamide, hydroxychlorzoxazone, and 4-acetamidophenol were purchased from Toronto Research Chemicals (Toronto, Canada). Reduced nicotinamide adenine dinucleotide phosphate (NADPH) was acquired from Roche Pharmaceuticals Ltd. (Basel, Switzerland). Ultra-pure water was produced by Milli-Q, a reagent-standard water purification system (Millipore, Bedford, USA). Acetonitrile and methanol that of high performance liquid chromatography (HPLC) grade were obtained from Merck Company (Darmstadt, Germany).
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