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Veliparib

Manufactured by Cayman Chemical
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Veliparib is a lab equipment product manufactured by Cayman Chemical. It is a small molecule compound that functions as a poly(ADP-ribose) polymerase (PARP) inhibitor. The core function of Veliparib is to inhibit PARP activity, which is involved in DNA repair processes.

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Lab products found in correlation

Cisplatin, by Merck Group (1 mentions) Oxaliplatin, by Merck Group (1 mentions) Carboplatin, by Merck Group (1 mentions) Selinexor, by Selleck Chemicals (1 mentions) Cryptotanshinone, by Selleck Chemicals (1 mentions) Cb 839, by Selleck Chemicals (1 mentions) Rvx 208, by Selleck Chemicals (1 mentions) Ly2603618, by Selleck Chemicals (1 mentions) Spautin 1, by Selleck Chemicals (1 mentions) Ferrostatin 1, by Selleck Chemicals (1 mentions) Mitomycin c, by Selleck Chemicals (1 mentions) Liproxstatin 1, by Selleck Chemicals (1 mentions) Hydrogen peroxide h2o2, by Merck Group (1 mentions) Methyl methanesulfonate mms, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Xav939, by Merck Group (1 mentions) Olaparib, by Cayman Chemical (1 mentions) Pdd00017273, by Merck Group (1 mentions)

2 protocols using veliparib

1

Comprehensive Anticancer Compound Evaluation

Cited 1 time
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CB-839, mitomycin C, cryptotanshinone, altretamine, GSK583, liproxstatin-1, spautin-1, PD-1/PD-L1 inhibitor 2, RVX-208, selinexor, ferrostatin-1, diacerein, LY2603618, and patupilone were purchased from Selleckchem (Houston, TX). Cisplatin, carboplatin and oxaliplatin were purchased from Sigma-Aldrich (St. Louis, MO). Olaprib, niraparib, veliparib were purchased from Cayman Chemical (Ann Arbor, MI). As2O3 was purchased from BioTang (Lexington, MA). C1–27 is a GSTO1 inhibitor previously identified and synthesized by our laboratory (5 (link)).
Xu Y., Bankhead A I.I.I., Tian X., Tang J., Ljungman M, & Neamati N. (2020). Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor. Cancer research, 80(17), 3692-3705.
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2

PARP Inhibitor Treatments Optimization

Check if the same lab product or an alternative is used in the 5 most similar protocols
PARP inhibitors Olaparib, Talazoparib and Veliparib were purchased from Cayman Chemical or Enzo Life Sciences; Niraparib, Rucaparib and ME0328 from Stratech Scientific; XAV-939 and PDD00017273 from Sigma-Aldrich, and were dissolved in dimethyl sulfoxide (DMSO) (Sigma-Aldrich). Methyl methanesulfonate (MMS) and hydrogen peroxide (H2O2) were obtained from Sigma-Aldrich. Concentrations and durations of treatment are indicated in the sections below and in the respective figures.
Prokhorova E., Zobel F., Smith R., Zentout S., Gibbs-Seymour I., Schützenhofer K., Peters A., Groslambert J., Zorzini V., Agnew T., Brognard J., Nielsen M.L., Ahel D., Huet S., Suskiewicz M.J, & Ahel I. (2021). Serine-linked PARP1 auto-modification controls PARP inhibitor response. Nature Communications, 12, 4055.
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