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Deferoxamine mesylate

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Deferoxamine mesylate is a chelating agent used to remove excess iron from the body. It binds to iron and facilitates its excretion through urine, stool, and sweat. Deferoxamine mesylate is primarily used to treat iron overload conditions such as hemochromatosis and thalassemia.

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Lab products found in correlation

Docetaxel, by Merck Group (1 mentions) Chloroquine, by Merck Group (1 mentions) Trolox, by Santa Cruz Biotechnology (1 mentions) Wortmannin, by Merck Group (1 mentions) Mouse anti galectin 3, by Santa Cruz Biotechnology (1 mentions) Z vad fmk, by Apexbio (1 mentions) Acridine orange, by Thermo Fisher Scientific (1 mentions) Bafilomycin a1, by Bio-Techne (1 mentions) Paclitaxel, by Merck Group (1 mentions) N acetyl l cysteine, by Merck Group (1 mentions) Ferrostatin 1, by Merck Group (1 mentions) Citric acid, by Thermo Fisher Scientific (1 mentions) Enterobactin, by Merck Group (1 mentions) Ciprofloxacin hcl, by GoldBio (1 mentions) Gallium 3 nitrate, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Sodium hydroxide (naoh), by Merck Group (1 mentions) Acetonitrile, by Merck Group (1 mentions) Hydrochloric acid (hcl), by Merck Group (1 mentions) Sodium phosphate dibasic, by Merck Group (1 mentions)

2 protocols using deferoxamine mesylate

1

Autophagy and Oxidative Stress Regulation

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Rabbit anti-LC3B (L7543), mouse anti-βActin (A5441), N-Acetyl-L-cysteine (A9165) were from Sigma. Mouse anti-p62 (D-3, sc-28359), mouse anti-Lamp1 (H4A3, sc-20011), mouse anti-HIF-1α (28b, sc-13515), rabbit anti-Cathepsin B (sc-6493), mouse anti-Galectin 3 (sc-32790), DL-α-Tocopherol (sc-294383A), H-Leu-Leu-OMe Hydrochloride (sc-285992A), Trolox (sc-200810), Ferrocene (sc-353607), Deferoxamine mesylate (sc-203331) were from Santa Cruz Biotechnology. Rabbit anti-PARP (9542S) were from Cell Signaling. Acridine orange (A-3568) was from Life Technologies. Bafilomycin A1 (1334) was from Tocris. Chloroquine (C6628), Wortmannin (W1628), Ferrostatin-1 (SML0583), Necrostatin-1 (N9037), Cisplatin (P4394), Docetaxel (01885), Doxorubicin (D1515), Paclitaxel (T7402) were from Sigma. Phenethyl isothiocyanate (PEITC, 253731) was from Aldrich. E-64-D (BML-PI107), Pepstatin A (ALX-260-085) were from Enzo Life Sciences. Z-VAD-FMK (A1902) was from APExBIO. Ferroquine and amino-ferrocene were provided by Prof. Christophe Biot, University Lille1, France.
Kondratskyi A., Kondratska K., Vanden Abeele F., Gordienko D., Dubois C., Toillon R.A., Slomianny C., Lemière S., Delcourt P., Dewailly E., Skryma R., Biot C, & Prevarskaya N. (2017). Ferroquine, the next generation antimalarial drug, has antitumor activity. Scientific Reports, 7, 15896.
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2

Characterization of Bacterial Siderophores

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Tannic acid (TA, ACS reagent grade), enterobactin (derived from Escherichia coli, ≥98%), diethyl ether (ACS reagent grade, 99%), acetonitrile (HPLC grade, 99.9%), sodium hydroxide (NaOH; ACS reagent grade, 97%), hydrochloric acid (HCl, ACS reagent, 37%), sodium phosphate dibasic (Na2HPO4; ACS reagent grade, 99%), Gallium (III) nitrate (99.9%), and dimethyl sulfoxide (DMSO; BioReagent grade, 99.9%) were all purchased from Sigma Aldrich (Milwaukee, WI). Citric acid (99%), iron (III) sulfate pentahydrate (97%), and sodium molybdate (VI) dihydrate (99%) were purchased from Acros Organic (New Jersey, US). Sodium nitrite (lab grade, 99%) was obtained from Ward’s Science+ (Rochester, NY). Deferoxamine mesylate (DFO, 97%) was purchased from Santa Cruz Biotechnology Inc. (Dallas, TX). Ciprofloxacin HCl (molecular biology grade) was purchased from GoldBio (St. Louis, MO). Sodium alginate was obtained from Spectrum Chemical (New Brunswick, NJ). Phosphate-buffered saline (PBS, pH = 7.4, ionic strength = 154 mM) was prepared by diluting commercially available liquid concentrate (OmniPur® 10X PBS) purchased from EMD Millipore (Burlington, MA). BacTiter-Glo™ microbial cell viability assay was purchased from Promega (Madison, WI). All chemicals were used as received unless otherwise noted.
Ortiz B.J., Jennings J., Gross W.S., Santos T.M., Lin T.Y., Weibel D.B, & Lynn D.M. (2021). Soft Materials that Intercept, Respond to, and Sequester Bacterial Siderophores. Chemistry of materials : a publication of the American Chemical Society, 33(13), 5401-5412.
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