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SiRNA II is a laboratory equipment product designed for the delivery of small interfering RNA (siRNA) into cells. It enables the targeted silencing of gene expression, allowing researchers to investigate the functional roles of specific genes.

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Lab products found in correlation

Akt sirna 1, by Cell Signaling Technology (2 mentions) Lipofectamine 2000 transfection reagent, by Thermo Fisher Scientific (2 mentions)

Spelling variants of this product

ERK1/2 siRNA (10 citations) SignalSilence® p44/42 MAPK (Erk1/2) siRNA (5 citations) SiRNAs (4 citations) SignalSilence® Stat3 siRNA II (3 citations) SignalSilence® p38α MAPK siRNA II (2 citations) P44/42 MAPK (ERK1/2) siRNA (2 citations) β-catenin siRNA II (2 citations) AKT1/2 siRNA (2 citations)

2 protocols using sirna 2

1

Silencing Key Signaling Molecules

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
The non-silencing (control), rictor, raptor, GSK3α/β and FBXW7 siRNAs were the same as described previously 22 (link). Akt siRNA I (#6211) that targets Akt1 and Akt2 and siRNA II (#6510) that targets Akt1 were purchased from Cell Signaling (Beverly, MA). Transfection of these siRNA duplexes was conducted in 6-well plates using the Lipofectamine 2000 transfection reagent (Invitrogen, Carlsbad, CA) following the manufacturer’s manual.
Li S., Oh Y.T., Yue P., Khuri F.R, & Sun S.Y. (2015). Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells. Oncogene, 35(5), 642-650.
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2

Silencing Key Signaling Molecules

Cited 1 time
Check if the same lab product or an alternative is used in the 5 most similar protocols
The non-silencing (control), rictor, raptor, GSK3α/β and FBXW7 siRNAs were the same as described previously 22 (link). Akt siRNA I (#6211) that targets Akt1 and Akt2 and siRNA II (#6510) that targets Akt1 were purchased from Cell Signaling (Beverly, MA). Transfection of these siRNA duplexes was conducted in 6-well plates using the Lipofectamine 2000 transfection reagent (Invitrogen, Carlsbad, CA) following the manufacturer’s manual.
Li S., Oh Y.T., Yue P., Khuri F.R, & Sun S.Y. (2015). Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells. Oncogene, 35(5), 642-650.
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