1 naphthol

Purified water from an Elix 3 UV Water Purification System (Merck, Darmstadt, Germany) was used. All reagents were commercially available and of analytical grade. 1-Naphthol, 1-naphthalenesulfonic acid (1-NS), 2,6-naphthalenedisulfonic acid (2,6-NDS), 1,3,6-naphthalenetrisulfonic acid (1,3,6-NTS), Eosin Y, perylene, acetonitrile, and ethyl acetate were purchased from FUJIFILM Wako Pure Chemical Co. (Osaka, Japan). Fused-silica capillary tubes with an inner diameter of 75 μm (and an outer diameter of 150 μm) were purchased from GL Science Co. (Tokyo, Japan).

Purified water obtained from an Elix 3 UV water purification system (Millipore Co., Billerica, MA) was used. All reagents were commercially available and of analytical grade and include 1-naphthol, 1-naphthalenesulfonic acid (1-NS), 2,6-naphthalenedisulfonic acid (2,6-NDS), 1,3,6-naphthalenetrisulfonic acid (1,3,6-NTS), Eosin Y, perylene, acetonitrile, and ethyl acetate from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). Fused-silica capillary tubes with an inner diameter of 50 μm and an outer diameter of 375 μm were purchased from GL Science Co. (Tokyo, Japan). In order to maintain the absorption sensitivity constant that depends on a capillary inner diameter or light length and hold the same length of sample zone in a capillary tube, we determined the capillary inner diameter to be 50 μm in this study.

Methiocarb, carbaryl, 1-naphthol, methiocarb sulfoxide, methiocarb sulfone, 4-methylthio-3,5-xylenol (MX), 3,5-dimethyl-4-(methylsulfinyl)phenol (SP), 3,5-dimethyl-4-(methylsulfonyl)phenol (SOP), menadione, 2-hydroxypyrimidine, rat albumin and human albumin were purchased from Wako Pure Chemical Industries (Osaka, Japan). Eserine, 2-chloro-3,4-dimethoxybenzyl (CDMB), bis(4-nitrophenyl)phosphate (BNPP), 5-pregnen-3β-ol-20-one-16α-carbonitrile (PCN), artemisinin, and bezafibrate (BZF) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Infinity pure dimethyl sulfoxide (DMSO; > 99.5% pure) was purchased from Wako Pure Chemical Industries. Human recombinant CYP and FMO isoforms expressed in a baculovirus system and pooled human plasma were purchased from BD Gentest (Woburn, MA, USA).